INT151826

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 3.38
Pain Relevance 2.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnf, TNF) extracellular space (Tnf, TNF) extracellular region (Tnf, TNF)
plasma membrane (Tnf, TNF) intracellular (Tnf, TNF) extracellular matrix organization (Tnf, TNF)
Tnf (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
nociceptor 10 99.78 Very High Very High Very High
qutenza 4 99.78 Very High Very High Very High
Hyperalgesia 12 98.64 Very High Very High Very High
Pain 2 93.60 High High
antagonist 2 81.12 Quite High
Etanercept 2 80.68 Quite High
Kinase C 2 64.44 Quite High
Disease Link Frequency Relevance Heat
Cancer 18 100.00 Very High Very High Very High
Necrosis 6 100.00 Very High Very High Very High
Hyperalgesia 12 98.64 Very High Very High Very High
Pain 2 93.60 High High
Metastasis 2 91.88 High High
Targeted Disruption 2 88.84 High High
Nociception 2 76.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model.
TNFalpha Positive_regulation (requires) of TNF associated with necrosis, hyperalgesia, qutenza and cancer
1) Confidence 0.04 Published 2008 Journal J. Neurosci. Section Title Doc Link 18463260 Disease Relevance 1.69 Pain Relevance 1.25
Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model.
tumor necrosis factor alpha Positive_regulation (requires) of TNF associated with necrosis, hyperalgesia, qutenza and cancer
2) Confidence 0.04 Published 2008 Journal J. Neurosci. Section Title Doc Link 18463260 Disease Relevance 1.69 Pain Relevance 1.26

General Comments

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