INT151835

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Context Info
Confidence 0.48
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (UBE4B) enzyme binding (UBE4B) cytoplasm (UBE4B)
UBE4B (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 1 75.52 Quite High
Disease Link Frequency Relevance Heat
Frailty 1 96.96 Very High Very High Very High
Osteoporosis 1 95.32 Very High Very High Very High
Breast Cancer 1 91.56 High High
Reprotox - General 1 1 84.32 Quite High
Hypoactive Sexual Desire Disorder 1 82.96 Quite High
Wrinkles 1 78.88 Quite High
Immune System Diseases 1 76.88 Quite High
Headache 1 75.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on its safety data, its pharmacokinetic properties, its pharmacological profile and the results of first human studies, E4 may be suitable as a potential drug for human use in applications such as hormone replacement therapy (vaginal atrophy, hot flushes), contraception and osteoporosis.
Positive_regulation (drug) of E4 associated with frailty and osteoporosis
1) Confidence 0.48 Published 2008 Journal Climacteric Section Abstract Doc Link 18464023 Disease Relevance 0.68 Pain Relevance 0.08

General Comments

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