INT151847

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 4.53
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lamc2) proteinaceous extracellular matrix (Lamc2)
Lamc2 (Mus musculus)
Pain Link Frequency Relevance Heat
Dismenorea 9 99.06 Very High Very High Very High
Neuronal excitability 5 92.80 High High
depression 1 76.80 Quite High
gABA 2 75.00 Quite High
hyperexcitability 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Dysmenorrhea 8 99.06 Very High Very High Very High
Clear Cell Adenocarcinoma 16 99.04 Very High Very High Very High
Cancer 28 98.26 Very High Very High Very High
Convulsion 1 92.00 High High
Anxiety Disorder 1 89.04 High High
Cyst 4 88.08 High High
Stress 1 85.76 High High
Post-partum Depression 1 76.80 Quite High
Reprotox - General 1 1 75.48 Quite High
Epilepsy 1 74.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When non-invasive tumor cells were considered to be at an early stage in tumor progression, some tumor cells had already acquired an invasive feature. p53 overexpression was not related to expression of the laminin-5 gamma2 chain.
Gene_expression (expression) of laminin-5 gamma2 chain associated with cancer
1) Confidence 0.14 Published 2008 Journal Pathol. Res. Pract. Section Abstract Doc Link 18467037 Disease Relevance 1.07 Pain Relevance 0.13
Clear cell adenocarcinoma arising from a giant cystic adenomyosis: a case report with immunohistochemical analysis of laminin-5 gamma2 chain and p53 overexpression.
Gene_expression (overexpression) of laminin-5 gamma2 chain associated with clear cell adenocarcinoma and dismenorea
2) Confidence 0.14 Published 2008 Journal Pathol. Res. Pract. Section Title Doc Link 18467037 Disease Relevance 1.03 Pain Relevance 0.20
We report a case of a clear cell adenocarcinoma arising from a giant cystic adenomyosis, with immunohistochemical analysis of p53 and laminin-5 gamma2 chain overexpression.
Gene_expression (overexpression) of laminin-5 gamma2 chain associated with clear cell adenocarcinoma and dismenorea
3) Confidence 0.14 Published 2008 Journal Pathol. Res. Pract. Section Abstract Doc Link 18467037 Disease Relevance 0.85 Pain Relevance 0.17
Laminin-5 gamma2 chain expression was low in papillary proliferation and high in myometrial invasion and metastatic foci.
Gene_expression (expression) of Laminin-5 gamma2 chain
4) Confidence 0.12 Published 2008 Journal Pathol. Res. Pract. Section Abstract Doc Link 18467037 Disease Relevance 1.00 Pain Relevance 0.15
A moderate and brief exposure to elevated neurosteroids, such as those that occur over the ovarian cycle and following an acute stressful episode, result in a decrease in GABAAR gamma2 subunit expression and an increase in GABAAR delta subunit expression.
Gene_expression (expression) of gamma2 subunit
5) Confidence 0.06 Published 2009 Journal Psychoneuroendocrinology Section Abstract Doc Link 19632051 Disease Relevance 0.57 Pain Relevance 0.31

General Comments

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