INT151903

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.53
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PLG) extracellular space (PLG) extracellular region (PLG)
plasma membrane (PLG)
PLG (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 47 93.16 High High
antagonist 4 80.40 Quite High
Somatostatin 8 59.76 Quite High
Inflammation 14 50.72 Quite High
endometriosis 3 28.64 Quite Low
pain pelvic 1 25.00 Low Low
cva 4 15.60 Low Low
positron emission tomography 16 5.00 Very Low Very Low Very Low
cINOD 16 5.00 Very Low Very Low Very Low
Glutamate 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 60 98.76 Very High Very High Very High
Amyloid Plaque 14 94.32 High High
Cancer 24 92.16 High High
Diabetes Mellitus 2 74.28 Quite High
Disease 248 71.80 Quite High
Metabolic Syndrome 1 71.68 Quite High
Drug Induced Neurotoxicity 2 68.08 Quite High
Cognitive Disorder 56 55.04 Quite High
Adhesions 1 53.52 Quite High
INFLAMMATION 16 50.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activation of plasminogen into plasmin is mediated by two types of activators, urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA).
Positive_regulation (mediated) of Positive_regulation (activation) of plasmin
1) Confidence 0.45 Published 2008 Journal Curr. Med. Chem. Section Abstract Doc Link 18473800 Disease Relevance 0.22 Pain Relevance 0
These data demonstrate that breast cancer cells dissolve type I collagen and that there is an absolute requirement for plasminogen activation and MMP activity in the degradation process.



Positive_regulation (requirement) of Positive_regulation (activation) of plasminogen associated with breast cancer
2) Confidence 0.36 Published 2005 Journal Cancer Cell Int Section Abstract Doc Link PMC548674 Disease Relevance 0.38 Pain Relevance 0.24
Stimulation of plasminogen through tPA (tissue plasminogen activator) and the subsequent generation of plasmin reduces ?
Positive_regulation (Stimulation) of Positive_regulation (activator) of plasminogen
3) Confidence 0.03 Published 2009 Journal The Open Neurology Journal Section Body Doc Link PMC2684708 Disease Relevance 0.47 Pain Relevance 0.12
Stimulation of plasminogen through tPA (tissue plasminogen activator) and the subsequent generation of plasmin reduces ?
Positive_regulation (Stimulation) of Positive_regulation (Stimulation) of plasminogen
4) Confidence 0.03 Published 2009 Journal The Open Neurology Journal Section Body Doc Link PMC2684708 Disease Relevance 0.46 Pain Relevance 0.12

General Comments

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