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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.46
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ccr7) plasma membrane (Ccr7) intracellular (Ccr7)
signal transducer activity (Ccr7)
Anatomy Link Frequency
T-cell 1
Ccr7 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 46 100.00 Very High Very High Very High
opioid receptor 6 100.00 Very High Very High Very High
Opioid 3 96.08 Very High Very High Very High
Enkephalin 1 92.76 High High
agonist 1 90.56 High High
chemokine 5 77.92 Quite High
Delta opioid receptors 1 75.00 Quite High
Inflammation 45 71.68 Quite High
Endogenous opioid 1 69.68 Quite High
tolerance 2 27.56 Quite Low
Disease Link Frequency Relevance Heat
Dengue 64 98.56 Very High Very High Very High
Infection 23 98.28 Very High Very High Very High
Disease 24 97.28 Very High Very High Very High
Viral Infection 5 75.44 Quite High
INFLAMMATION 47 71.68 Quite High
Dengue Hemorrhagic Fever 31 61.28 Quite High
Apoptosis 7 38.48 Quite Low
Hypersensitivity 15 5.00 Very Low Very Low Very Low
Arthritis 13 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cross-talk between CCR7 and DOR receptors that are both up-regulated during DC maturation was then examined.
Positive_regulation (up-regulated) of CCR7 associated with opioid receptor
1) Confidence 0.47 Published 2008 Journal J. Neuroimmunol. Section Abstract Doc Link 18486241 Disease Relevance 0.07 Pain Relevance 0.86
Twist1 expression is enhanced in CCR7?
Positive_regulation (enhanced) of CCR7
2) Confidence 0.35 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2525589 Disease Relevance 0 Pain Relevance 0
In addition to increases in cytokine levels cellular markers for T-cell activation, CD69, CD38, and CCR7 have been shown to be increased in dengue infection[33] and IFN?
Positive_regulation (increases) of CCR7 in T-cell associated with dengue, infection and cytokine
3) Confidence 0.23 Published 2009 Journal Virol J Section Body Doc Link PMC2789730 Disease Relevance 1.38 Pain Relevance 0.29

General Comments

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