INT152058

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.53
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2l1) intracellular (Bcl2l1) response to stress (Bcl2l1)
cytoplasm (Bcl2l1) cytosol (Bcl2l1) cell proliferation (Bcl2l1)
Anatomy Link Frequency
retina 2
hippocampus 2
Bcl2l1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 3 99.68 Very High Very High Very High
Clonidine 2 98.94 Very High Very High Very High
ischemia 32 93.12 High High
agonist 2 83.36 Quite High
antagonist 1 81.28 Quite High
Central nervous system 2 10.64 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 4 93.12 High High
Apoptosis 33 89.44 High High
Death 7 80.16 Quite High
Retina Disease 17 53.20 Quite High
Ganglion Cysts 3 48.72 Quite Low
Glaucoma 1 44.68 Quite Low
Targeted Disruption 2 19.36 Low Low
Ocular Hypertension 8 11.88 Low Low
Cv Unclassified Under Development 11 10.72 Low Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, our results showing a time-related decrease in Bcl-xL expression in the retina following I/R are in conflict with a publication on hippocampal neurons, where no alteration of the abundance of Bcl-xL was observed following I/R [27].
Neg (no) Regulation (alteration) of Transcription (abundance) of Bcl-xL in retina
1) Confidence 0.32 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2765238 Disease Relevance 0.46 Pain Relevance 0.05
Administration of clonidine 20 min after yohimbine administration abolished its effect on Bcl-XL mRNA level in the hippocampus.
Regulation (effect) of Transcription (level) of Bcl-XL in hippocampus associated with hippocampus and clonidine
2) Confidence 0.27 Published 2008 Journal Izv. Akad. Nauk. Ser. Biol. Section Abstract Doc Link 18491567 Disease Relevance 0.07 Pain Relevance 0.45

General Comments

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