INT152069

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Context Info
Confidence 0.60
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.15
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Anxa2) extracellular region (Anxa2) plasma membrane (Anxa2)
protein complex (Anxa2) cytoplasm (Anxa2)
Anxa2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 6 94.88 High High
Neuropathic pain 4 93.68 High High
Kinase C 1 79.64 Quite High
cytokine 2 71.04 Quite High
neuralgia 3 25.00 Low Low
Tetrahydrobiopterin 8 5.00 Very Low Very Low Very Low
diabetic neuropathy 8 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 94.88 High High
Neuropathic Pain 10 93.68 High High
Shock 1 83.16 Quite High
Diabetes Complications 12 83.00 Quite High
Stress 84 80.96 Quite High
Diabetes Mellitus 182 78.72 Quite High
Hyperglycemia 16 74.60 Quite High
Cardiovascular Disease 20 5.00 Very Low Very Low Very Low
Myocardial Infarction 18 5.00 Very Low Very Low Very Low
Diabetic Neuropathy 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, real-time quantitative RT-PCR experiments indicated that CCD-induced increase in protein levels was associated with an up-regulation of annexin A2 and PKCepsilon gene expression.
Gene_expression (expression) of annexin A2
1) Confidence 0.60 Published 2008 Journal Exp Brain Res Section Abstract Doc Link 18493752 Disease Relevance 0.74 Pain Relevance 0.56
What is more important is that blockade of •O2- radicals by three different approaches using either a small molecule uncoupler of mitochondrial oxidative phosphorylation (CCCP), overexpression of uncoupling protein-1 (UCP1) or overexpression of Mn-SOD, prevented changes in NF-?
Gene_expression (overexpression) of protein-1
2) Confidence 0.01 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1131912 Disease Relevance 0.71 Pain Relevance 0.03
What is more important is that blockade of •O2- radicals by three different approaches using either a small molecule uncoupler of mitochondrial oxidative phosphorylation (CCCP), overexpression of uncoupling protein-1 (UCP1) or overexpression of Mn-SOD, prevented changes in NF-?
Gene_expression (overexpression) of protein-1
3) Confidence 0.01 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1131912 Disease Relevance 0.71 Pain Relevance 0.04

General Comments

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