INT152125

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Context Info
Confidence 0.57
First Reported 2008
Last Reported 2010
Negated 4
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.28
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Prph)
Anatomy Link Frequency
peripheral nerves 6
neurons 2
skin 2
heart 2
Prph (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 13 96.52 Very High Very High Very High
dorsal root ganglion 103 95.88 Very High Very High Very High
adenocard 13 95.40 Very High Very High Very High
Sciatic nerve 13 90.76 High High
Peripheral nerve injury 17 67.60 Quite High
Neuropeptide 6 60.44 Quite High
imagery 16 57.80 Quite High
Angina 2 53.16 Quite High
Inflammation 55 50.00 Quite Low
Spinal cord 9 47.20 Quite Low
Disease Link Frequency Relevance Heat
Stress 17 99.76 Very High Very High Very High
Nociception 17 96.16 Very High Very High Very High
Ganglion Cysts 103 95.88 Very High Very High Very High
Body Weight 3 88.08 High High
Injury 5 83.72 Quite High
Nervous System Injury 31 80.28 Quite High
Aging 4 75.00 Quite High
Phobia 1 55.52 Quite High
Obstructive Airway Disease 1 54.80 Quite High
Cv General 3 Under Development 2 53.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the levels of peripherin, NGF isoforms and TrkA in skin, peripheral nerves and DRG, respectively, were not significantly reduced in aged rats.
Neg (not) Negative_regulation (reduced) of Gene_expression (levels) of peripherin in peripheral nerves
1) Confidence 0.57 Published 2010 Journal Neurobiol. Aging Section Abstract Doc Link 18499304 Disease Relevance 0.32 Pain Relevance 0
However, the levels of peripherin, NGF isoforms and TrkA in skin, peripheral nerves and DRG, respectively, were not significantly reduced in aged rats.
Neg (not) Negative_regulation (reduced) of Gene_expression (isoforms) of peripherin in peripheral nerves
2) Confidence 0.41 Published 2010 Journal Neurobiol. Aging Section Abstract Doc Link 18499304 Disease Relevance 0.32 Pain Relevance 0
However, the levels of peripherin, NGF isoforms and TrkA in skin, peripheral nerves and DRG, respectively, were not significantly reduced in aged rats.
Neg (not) Negative_regulation (reduced) of in skin Gene_expression (levels) of peripherin in peripheral nerves
3) Confidence 0.19 Published 2010 Journal Neurobiol. Aging Section Abstract Doc Link 18499304 Disease Relevance 0.32 Pain Relevance 0
However, the levels of peripherin, NGF isoforms and TrkA in skin, peripheral nerves and DRG, respectively, were not significantly reduced in aged rats.
Neg (not) Negative_regulation (reduced) of in skin Gene_expression (isoforms) of peripherin in peripheral nerves
4) Confidence 0.14 Published 2010 Journal Neurobiol. Aging Section Abstract Doc Link 18499304 Disease Relevance 0.32 Pain Relevance 0
Although the percentage of PAP-II-positive neurons expressing peripherin was slightly decreased (from 54.6 ± 10.3% to 48.7 ± 8.7%), co-expression of PAP-II and peripherin was still present in small DRG neurons (Fig. 7A and 7B).
Negative_regulation (decreased) of Gene_expression (expressing) of peripherin in neurons associated with dorsal root ganglion
5) Confidence 0.12 Published 2010 Journal Mol Pain Section Body Doc Link PMC2873504 Disease Relevance 1.47 Pain Relevance 0.88
First pass stress perfusion (PERF) (SSFP, TE/TR/FA 2.7/1.4/50°, 1 saturation prepulse per slice, 3 short axis slices/heart beat) was begun after 3 minutes of i.v. adenosine infusion (140 ?
Negative_regulation (/) of Gene_expression (/) of PERF in heart associated with stress and adenocard
6) Confidence 0.03 Published 2008 Journal J Cardiovasc Magn Reson Section Body Doc Link PMC2575198 Disease Relevance 0.54 Pain Relevance 0.13

General Comments

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