INT152145

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Context Info
Confidence 0.61
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.07
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp7) extracellular region (Mmp7) proteinaceous extracellular matrix (Mmp7)
Mmp7 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 11 100.00 Very High Very High Very High
cINOD 5 98.20 Very High Very High Very High
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenoma 2 99.84 Very High Very High Very High
Adhesions 28 98.32 Very High Very High Very High
INFLAMMATION 8 98.00 Very High Very High Very High
Cancer 13 94.68 High High
Colon Cancer 1 93.52 High High
Familial Adenomatous Polyposis 1 87.44 High High
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 3 5.00 Very Low Very Low Very Low
Chlamydia Infection 2 5.00 Very Low Very Low Very Low
Fibrosarcoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice.
Regulation (alters) of Gene_expression (expression) of matrilysin associated with adenoma
1) Confidence 0.61 Published 2008 Journal Carcinogenesis Section Title Doc Link 18499699 Disease Relevance 0.81 Pain Relevance 0.20
Synthesis of MMPs such as collagenase I (MMP-1), gelatinase B (MMP-9) and matrilysin (MMP-7) has been shown to be dependent on the synthesis of PG E2, suggesting that alterations in MMP expression may be instigated by alterations in PG synthesis [27,28,29,30].
Regulation (dependent) of Gene_expression (Synthesis) of MMP-7 associated with metalloproteinase
2) Confidence 0.07 Published 2001 Journal BMC Biochem Section Body Doc Link PMC31925 Disease Relevance 0.26 Pain Relevance 0.05

General Comments

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