INT152190

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
cell-cell signaling (IL2)
Anatomy Link Frequency
brain 2
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 12 99.76 Very High Very High Very High
withdrawal 3 99.48 Very High Very High Very High
cytokine 7 78.88 Quite High
opiate 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Neurological Disease 1 71.64 Quite High
Necrosis 1 63.84 Quite High
Cancer 1 63.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas chronic morphine treatment (48 h after implantation of 75 mg morphine pellets) and withdrawal from morphine (10-15 min after an i.p. injection of 1mg/kg of naltroxone 48 h after implantation of 75 mg morphine pellets) did not alter blood-to-brain transport of IL-1alpha or TNF-alpha, both the chronic morphine treatment and withdrawal from morphine groups had increased blood-to-brain transport of IL-2.
Positive_regulation (increased) of Phosphorylation (transport) of IL-2 in brain associated with withdrawal and morphine
1) Confidence 0.23 Published 2008 Journal Brain Behav. Immun. Section Abstract Doc Link 18502094 Disease Relevance 0.20 Pain Relevance 1.41

General Comments

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