INT152239

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mapk1, Nfkb1) protein complex (Mapk1, Nfkb1) cytoplasm (Mapk1, Nfkb1)
cytosol (Mapk1, Nfkb1) signal transduction (Mapk1, Nfkb1) nucleus (Mapk1, Nfkb1)
Anatomy Link Frequency
macrophages 2
Mapk1 (Mus musculus)
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
sodium channel 7 92.64 High High
tetrodotoxin 1 88.72 High High
Inflammatory response 1 64.44 Quite High
Disease Link Frequency Relevance Heat
Sepsis 1 65.00 Quite High
INFLAMMATION 1 64.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that LPS significantly increased the concentrations of TLR-4, NF-kappaB and MAPKs, including extracellular regulated kinase (ERK), c-jun N-terminal kinase (JNK) and p38 MAPK, in activated macrophages.
extracellular regulated kinase Positive_regulation (increased) of Localization (concentrations) of NF-kappaB in macrophages
1) Confidence 0.29 Published 2008 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 18505446 Disease Relevance 0.13 Pain Relevance 0.39

General Comments

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