INT152371

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.54
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grm1) nucleus (Grm1) signal transducer activity (Grm1)
Anatomy Link Frequency
nucleus accumbens 2
Grm1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 24 100.00 Very High Very High Very High
Nucleus accumbens 5 100.00 Very High Very High Very High
withdrawal 5 99.96 Very High Very High Very High
Pain 55 96.84 Very High Very High Very High
Morphine 4 94.00 High High
Glutamate 5 89.36 High High
Arthritis 29 58.96 Quite High
amygdala 55 50.00 Quite Low
GABAergic 16 14.88 Low Low
nMDA receptor antagonist 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 55 96.84 Very High Very High Very High
Arthritis 49 88.24 High High
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Like the mGluR1 antagonist, a selective mGluR5 antagonist (MTEP, 1 ?
Regulation (Like) of Gene_expression (antagonist) of mGluR1 associated with antagonist
1) Confidence 0.42 Published 2010 Journal Mol Pain Section Body Doc Link PMC3016348 Disease Relevance 0.54 Pain Relevance 0.56
Receptor density was evaluated after chronic treatment and after 1, 3, and 14 days of withdrawal. mGlu1 and mGlu5 expression in the nucleus accumbens and in the caudate putamen was not affected by any of the experimental manipulations.
Neg (not) Regulation (affected) of Gene_expression (expression) of mGlu1 in nucleus accumbens associated with nucleus accumbens and withdrawal
2) Confidence 0.04 Published 2008 Journal Neuroreport Section Abstract Doc Link 18520992 Disease Relevance 0 Pain Relevance 0.85

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox