INT152434

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 9.47
Pain Relevance 2.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL11) extracellular space (CCL11) extracellular region (CCL11)
cell adhesion (CCL11) cytoskeleton organization (CCL11)
Anatomy Link Frequency
myoblasts 2
monocyte 1
eosinophil 1
upper 1
CCL11 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 56 100.00 Very High Very High Very High
Fibrositis 26 99.04 Very High Very High Very High
Inflammation 181 99.00 Very High Very High Very High
dexamethasone 7 98.14 Very High Very High Very High
cytokine 57 88.88 High High
headache 2 64.80 Quite High
Inflammatory response 11 58.48 Quite High
bradykinin 2 28.24 Quite Low
aspirin 15 5.00 Very Low Very Low Very Low
Inflammatory mediators 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 20 99.04 Very High Very High Very High
INFLAMMATION 213 99.00 Very High Very High Very High
Rhinitis 259 98.48 Very High Very High Very High
Polyps 39 93.08 High High
Eczema 94 90.48 High High
Nasal Polyps 19 89.84 High High
Disease 83 89.20 High High
Asthma 188 89.04 High High
Chronic Sinusitis 43 89.00 High High
Hypersensitivity 33 88.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, myoblasts can secrete MCP-1, eotaxin, and IP-10, while treatment with MCP-1 caused secretion of IL-1beta, eotaxin and IP-10.
Localization (secretion) of eotaxin in myoblasts
1) Confidence 0.78 Published 2008 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 18535166 Disease Relevance 1.15 Pain Relevance 0.72
Furthermore, myoblasts can secrete MCP-1, eotaxin, and IP-10, while treatment with MCP-1 caused secretion of IL-1beta, eotaxin and IP-10.
Localization (secrete) of eotaxin in myoblasts
2) Confidence 0.68 Published 2008 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 18535166 Disease Relevance 1.15 Pain Relevance 0.71
Mediators (including histamine; cysteinyl leukotrienes; interleukin [IL]-4, IL-5, IL-13; regulated on activation, normal T-cell expressed and secreted [RANTES] chemokine; and eotaxin) are expressed in both upper and lower airways [14,15].
Localization (secreted) of eotaxin in upper associated with chemokine
3) Confidence 0.68 Published 2005 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2877070 Disease Relevance 1.65 Pain Relevance 0.18
The CCL18 gene is also located near the eotaxin-1 and MCP genes cluster at chromosome 17q11.2.
Localization (located) of eotaxin-1
4) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 1.11 Pain Relevance 0.26
These included increased transcription of chemokines localized to chromosome 17q11.2 (CCL13, CCL2, CCL8, and CCL11) that favor eosinophil and monocyte chemotaxis and chemokines (CCL18, CCL22, and CXCL13) that alternatively-activated monocyte-derived cells have been shown to produce.
Localization (localized) of CCL11 in monocyte associated with chemokine
5) Confidence 0.49 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2897889 Disease Relevance 1.82 Pain Relevance 0.17
To determine the expression of the chemokine Eotaxin in our cultures, we determined by qualitative immunofluorescent microscopy the localization of Eotaxin as well as MBP in human airways incubated 18?
Localization (localization) of Eotaxin associated with chemokine
6) Confidence 0.32 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2843899 Disease Relevance 0.34 Pain Relevance 0.08
Neither dexamethasone nor IL-10 inhibited the expression of mRNA encoding eotaxin, although IL-10 did inhibit the release of eotaxin protein into the culture medium, suggesting inhibition at a translational and/or post-translational level [32].


Localization (release) of eotaxin associated with dexamethasone
7) Confidence 0.25 Published 2002 Journal Respir Res Section Body Doc Link PMC64809 Disease Relevance 0.45 Pain Relevance 0.37
These included increased transcription of chemokines localized to chromosome 17q11.2 (CCL13, CCL2, CCL8, and CCL11) that favor eosinophil and monocyte chemotaxis and chemokines (CCL18, CCL22, and CXCL13) that alternatively-activated monocyte-derived cells have been shown to produce.
Localization (localized) of CCL11 in eosinophil associated with chemokine
8) Confidence 0.17 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2897889 Disease Relevance 1.82 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox