INT152435

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Context Info
Confidence 0.67
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 4.85
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL11) extracellular space (CCL11) extracellular region (CCL11)
cell adhesion (CCL11) cytoskeleton organization (CCL11)
Anatomy Link Frequency
monocyte 3
myoblasts 2
eosinophil 1
CCL11 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 15 100.00 Very High Very High Very High
Fibrositis 13 99.04 Very High Very High Very High
Inflammation 51 97.20 Very High Very High Very High
cytokine 5 88.88 High High
headache 1 62.32 Quite High
aspirin 10 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
cocaine 2 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 10 99.04 Very High Very High Very High
INFLAMMATION 55 97.20 Very High Very High Very High
Rhinitis 124 95.36 Very High Very High Very High
Polyps 26 94.60 High High
Eczema 62 92.00 High High
Asthma 34 77.16 Quite High
Chronic Sinusitis 28 75.00 Quite High
Disease 46 74.56 Quite High
Sleep Disorders 1 63.12 Quite High
Headache 1 62.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, myoblasts can secrete MCP-1, eotaxin, and IP-10, while treatment with MCP-1 caused secretion of IL-1beta, eotaxin and IP-10.
Positive_regulation (caused) of Localization (secretion) of eotaxin in myoblasts
1) Confidence 0.67 Published 2008 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 18535166 Disease Relevance 1.15 Pain Relevance 0.72
These included increased transcription of chemokines localized to chromosome 17q11.2 (CCL13, CCL2, CCL8, and CCL11) that favor eosinophil and monocyte chemotaxis and chemokines (CCL18, CCL22, and CXCL13) that alternatively-activated monocyte-derived cells have been shown to produce.
Positive_regulation (increased) of Localization (localized) of CCL11 in monocyte associated with chemokine
2) Confidence 0.32 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2897889 Disease Relevance 1.85 Pain Relevance 0.17
These included increased transcription of chemokines localized to chromosome 17q11.2 (CCL13, CCL2, CCL8, and CCL11) that favor eosinophil and monocyte chemotaxis and chemokines (CCL18, CCL22, and CXCL13) that alternatively-activated monocyte-derived cells have been shown to produce.
Positive_regulation (increased) of in eosinophil Localization (localized) of CCL11 in monocyte associated with chemokine
3) Confidence 0.11 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2897889 Disease Relevance 1.85 Pain Relevance 0.17

General Comments

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