INT152469

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 1.55
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (S100A1) intracellular (S100A1) protein complex (S100A1)
cytoplasm (S100A1)
Anatomy Link Frequency
brain 1
adipose tissue 1
Schwann cells 1
S100A1 (Homo sapiens)
S100A1 - S100A (1)
Pain Link Frequency Relevance Heat
Pain 1 81.20 Quite High
Central nervous system 6 50.00 Quite Low
iatrogenic 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 75 98.90 Very High Very High Very High
Pain 1 81.20 Quite High
Neurological Disease 6 72.96 Quite High
Stroke 3 69.20 Quite High
Injury 15 66.88 Quite High
Brain Injury 21 54.08 Quite High
Disease 16 28.08 Quite Low
Death 6 5.00 Very Low Very Low Very Low
Brain Tumor 6 5.00 Very Low Very Low Very Low
Hypertension 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nerve structures were detected by automatic immunostaining techniques using a polyclonal antibody against two S-100 proteins that reacts strongly with human S100A and B that are detected in Schwann cells.
S100A (S100A) Binding (reacts) of in Schwann cells
1) Confidence 0.36 Published 2008 Journal Neuroscience Section Abstract Doc Link 18538483 Disease Relevance 0.08 Pain Relevance 0.08
The clinical tests all measure total S100B, regardless of it monomeric or dimeric state, nor do they consider whether S100B is bound to S100B or S100A1.
S100A1 Spec (whether) Binding (bound) of
2) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2937027 Disease Relevance 0.13 Pain Relevance 0
Mass spectrometry of brain and adipose tissue confirmed the presence of S100B but also revealed the presence of S100A1.
S100A1 Binding (presence) of in adipose tissue associated with obesity
3) Confidence 0.24 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2937027 Disease Relevance 0.67 Pain Relevance 0
Mass spectrometry of brain and adipose tissue confirmed the presence of S100B but also revealed the presence of S100A1.
S100A1 Binding (presence) of in brain associated with obesity
4) Confidence 0.08 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2937027 Disease Relevance 0.67 Pain Relevance 0

General Comments

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