INT152539

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cx3cl1) extracellular region (Cx3cl1) plasma membrane (Cx3cl1)
cytoplasm (Cx3cl1)
Anatomy Link Frequency
microglia 2
Cx3cl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 4 99.96 Very High Very High Very High
Pain 6 97.68 Very High Very High Very High
Neuropathic pain 1 96.76 Very High Very High Very High
chemokine 1 92.64 High High
Peripheral nerve injury 1 88.32 High High
cytokine 1 82.64 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 99.96 Very High Very High Very High
Pain 4 97.68 Very High Very High Very High
Neuropathic Pain 2 96.76 Very High Very High Very High
Nervous System Injury 1 87.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although constitutively expressed and released during inflammation, increased release of fractalkine binds to and activates microglia leading to pathological pain.
Positive_regulation (increased) of Localization (release) of fractalkine in microglia associated with pain and inflammation
1) Confidence 0.34 Published 2008 Journal J. Neuroimmunol. Section Abstract Doc Link 18547654 Disease Relevance 0.90 Pain Relevance 0.75

General Comments

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