INT152541

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (PTGES) nucleoplasm (CBX1) signal transduction (PTGES)
nucleus (CBX1) enzyme binding (CBX1) cytoplasm (PTGES)
Anatomy Link Frequency
articular cartilage 2
CBX1 (Homo sapiens)
PTGES (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 4 50.00 Quite Low
cINOD 2 50.00 Quite Low
COX2 2 10.00 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Knee Osteoarthritis 3 75.68 Quite High
INFLAMMATION 2 71.80 Quite High
Osteoarthritis 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Both CBX and ACF inhibited COX-2, microsomal prostaglandin E synthase-1 (mPGES-1) and inducible nitric oxide synthase (iNOS) synthesis in the articular cartilage of OA patients.
CBX Negative_regulation (inhibited) of Gene_expression (synthesis) of prostaglandin E synthase-1 in articular cartilage
1) Confidence 0.15 Published 2008 Journal Osteoarthr. Cartil. Section Body Doc Link 18547825 Disease Relevance 0.30 Pain Relevance 0

General Comments

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