INT152560

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.73
Pain Relevance 1.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NOX1) oxidoreductase activity (NOX1) plasma membrane (NOX1)
response to stress (NOX1)
Anatomy Link Frequency
endothelial cells 1
aorta 1
heart 1
NOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 28 97.24 Very High Very High Very High
diclofenac 4 96.96 Very High Very High Very High
COX2 8 81.32 Quite High
Inflammation 17 32.72 Quite Low
ischemia 10 5.00 Very Low Very Low Very Low
cva 7 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 14 98.08 Very High Very High Very High
INFLAMMATION 23 84.44 Quite High
Stress 14 75.00 Quite High
Urological Neuroanatomy 9 63.28 Quite High
Increased Venous Pressure Under Development 4 25.00 Low Low
Disease 13 5.00 Very Low Very Low Very Low
Atherosclerosis 9 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 9 5.00 Very Low Very Low Very Low
Hemorrhage 6 5.00 Very Low Very Low Very Low
Edema 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of Nox1, Nox2, Nox4, and p22phox was increased markedly by the nonselective NSAIDs diclofenac or naproxen and moderately by rofecoxib or celecoxib in the aorta and heart of SHR.
Gene_expression (expression) of Nox1 in heart associated with cinod and diclofenac
1) Confidence 0.49 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18550689 Disease Relevance 0.33 Pain Relevance 0.74
The expression of Nox1, Nox2, Nox4, and p22phox was increased markedly by the nonselective NSAIDs diclofenac or naproxen and moderately by rofecoxib or celecoxib in the aorta and heart of SHR.
Gene_expression (expression) of Nox1 in aorta associated with cinod and diclofenac
2) Confidence 0.16 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18550689 Disease Relevance 0.33 Pain Relevance 0.74
of Nox1, Nox2, or Nox4 when overexpressed in endothelial cells.
Gene_expression (overexpressed) of Nox1 in endothelial cells
3) Confidence 0.15 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2593395 Disease Relevance 0.06 Pain Relevance 0

General Comments

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