INT152569

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NOX1) oxidoreductase activity (NOX1) plasma membrane (NOX1)
response to stress (NOX1)
Anatomy Link Frequency
heart 3
aorta 1
NOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 24 98.80 Very High Very High Very High
diclofenac 4 98.52 Very High Very High Very High
COX2 8 81.32 Quite High
Disease Link Frequency Relevance Heat
Hypertension 2 98.08 Very High Very High Very High
INFLAMMATION 4 84.44 Quite High
Stress 4 75.00 Quite High
Increased Venous Pressure Under Development 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of Nox1, Nox2, Nox4, and p22phox was increased markedly by the nonselective NSAIDs diclofenac or naproxen and moderately by rofecoxib or celecoxib in the aorta and heart of SHR.
Positive_regulation (increased) of Gene_expression (expression) of Nox1 in heart associated with cinod and diclofenac
1) Confidence 0.31 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18550689 Disease Relevance 0.33 Pain Relevance 0.75
The expression of Nox1, Nox2, Nox4, and p22phox was increased markedly by the nonselective NSAIDs diclofenac or naproxen and moderately by rofecoxib or celecoxib in the aorta and heart of SHR.
Positive_regulation (increased) of in aorta Gene_expression (expression) of Nox1 in heart associated with cinod and diclofenac
2) Confidence 0.11 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18550689 Disease Relevance 0.33 Pain Relevance 0.75

General Comments

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