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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Tnf) signal transduction (Tnf) extracellular space (Tnf)
extracellular region (Tnf) plasma membrane (Tnf) intracellular (Tnf)
Abmm (Mus musculus)
Tnf (Mus musculus)
Pain Link Frequency Relevance Heat
Infliximab 1 99.38 Very High Very High Very High
COX-2 inhibitor 2 84.88 Quite High
cINOD 1 66.40 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 3 88.96 High High
Rupture 1 88.08 High High
Injury 3 77.76 Quite High
INFLAMMATION 1 66.16 Quite High
Necrosis 1 61.28 Quite High
Cancer 1 60.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The concomitant administration of pentoxifylline (decreasing TNF-alpha secretion) and infliximab (trapping TNF-alpha) likewise attenuated the Jo2-mediated increase in TNF-alpha, the decrease in hepatic glutathione, and the increase in serum ALT activity 5 h after Jo2 administration.
Negative_regulation (attenuated) of Jo2-mediated Positive_regulation (increase) of TNF-alpha associated with infliximab
1) Confidence 0.01 Published 2008 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 18572215 Disease Relevance 0.64 Pain Relevance 0.20

General Comments

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