INT152765

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TAT, MYLK) mitochondrion (TAT) small molecule metabolic process (TAT)
enzyme binding (MYLK) cytoplasm (MYLK) biosynthetic process (TAT)
TAT (Homo sapiens)
MYLK (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 100.00 Very High Very High Very High
Inflammation 1 100.00 Very High Very High Very High
Morphine 3 99.84 Very High Very High Very High
opiate 3 84.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 1 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 8 91.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine and/or tat, via the activation of pro-inflammatory cytokines, intracellular Ca(2+) release, and activation of myosin light chain kinase, modulated TJ expression resulting in decreased transendothelial electric resistance and enhanced transendothelial migration across the BBB.
tat Regulation (modulated) of Positive_regulation (activation) of myosin light chain kinase associated with inflammation, cytokine and morphine
1) Confidence 0.40 Published 2008 Journal J. Clin. Immunol. Section Abstract Doc Link 18574677 Disease Relevance 0.66 Pain Relevance 0.60

General Comments

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