INT152779

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 6
Disease Relevance 4.64
Pain Relevance 2.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Hdis (Mus musculus)
Pain Link Frequency Relevance Heat
aspirin 42 100.00 Very High Very High Very High
cINOD 3 92.72 High High
Central nervous system 3 91.72 High High
peripheral neuropathy 3 78.88 Quite High
Inflammation 3 77.56 Quite High
Pain 3 77.00 Quite High
Disease Link Frequency Relevance Heat
Cancer 21 98.64 Very High Very High Very High
Death 12 98.34 Very High Very High Very High
Hemorrhage 3 93.52 High High
Hepatotoxicity 3 93.00 High High
INFLAMMATION 6 92.48 High High
Immunotherapy Of Cancer 3 85.84 High High
Ovarian Cancer 6 85.12 High High
Alopecia 3 81.36 Quite High
Vomiting 6 80.56 Quite High
Peripheral Neuropathy 3 78.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that HDIs and salicylic acid interacted synergistically, albeit less efficiently than HDIs and aspirin, to induce cancer cell death, suggesting that the acetyl and the salicyl moiety contributed to the cooperative interaction of aspirin with HDIs.
HDIs Binding (interacted) of associated with aspirin, cancer and death
1) Confidence 0.28 Published 2008 Journal Oncol. Rep. Section Abstract Doc Link 18575740 Disease Relevance 0.69 Pain Relevance 0.57
We found that HDIs and salicylic acid interacted synergistically, albeit less efficiently than HDIs and aspirin, to induce cancer cell death, suggesting that the acetyl and the salicyl moiety contributed to the cooperative interaction of aspirin with HDIs.
HDIs Binding (interaction) of associated with aspirin, cancer and death
2) Confidence 0.28 Published 2008 Journal Oncol. Rep. Section Abstract Doc Link 18575740 Disease Relevance 0.70 Pain Relevance 0.56
In this study, we investigated whether HDIs and aspirin interacted in inducing anticancer activity and histone acetylation.
HDIs Binding (interacted) of associated with aspirin
3) Confidence 0.28 Published 2008 Journal Oncol. Rep. Section Abstract Doc Link 18575740 Disease Relevance 0.41 Pain Relevance 0.42
These HDIs can be minimized or avoided by selecting herb-drug pairs which are less likely to interact.
HDIs Binding (minimized) of
4) Confidence 0.24 Published 2010 Journal Recent Pat Food Nutr Agric Section Abstract Doc Link 20653549 Disease Relevance 1.08 Pain Relevance 0.20
Severe herb-drug interactions (HDIs) have been recorded in some cases, and failure to recognize these harmful HDIs can lead to dire consequences in cancer patients.
HDIs Binding (interactions) of associated with cancer
5) Confidence 0.24 Published 2010 Journal Recent Pat Food Nutr Agric Section Abstract Doc Link 20653549 Disease Relevance 0.85 Pain Relevance 0.14
Severe herb-drug interactions (HDIs) have been recorded in some cases, and failure to recognize these harmful HDIs can lead to dire consequences in cancer patients.
HDIs Binding (recognize) of associated with cancer
6) Confidence 0.23 Published 2010 Journal Recent Pat Food Nutr Agric Section Abstract Doc Link 20653549 Disease Relevance 0.90 Pain Relevance 0.15

General Comments

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