INT152835

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Prkcg, Nfasc) cytosol (Prkcg) cell adhesion (Nfasc)
nucleus (Prkcg) intracellular (Prkcg) response to stress (Prkcg)
Prkcg (Rattus norvegicus)
Nfasc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
kinase C 5 100.00 Very High Very High Very High
induced neuropathy 3 99.48 Very High Very High Very High
Sciatic nerve 6 98.08 Very High Very High Very High
Spinal cord 5 97.80 Very High Very High Very High
Cerebral cortex 1 64.28 Quite High
Disease Link Frequency Relevance Heat
Drug Induced Neurotoxicity 1 100.00 Very High Very High Very High
Neuropathic Pain 3 58.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CaMKII and PKC might mediate the HD neurotoxicity by altering the NF phosphorylation status and PRs.
PKC Regulation (altering) of Phosphorylation (phosphorylation) of NF associated with kinase c and drug induced neurotoxicity
1) Confidence 0.10 Published 2008 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 18582483 Disease Relevance 0.21 Pain Relevance 0.87

General Comments

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