INT152869

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Context Info
Confidence 0.46
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tnf, Trpv1) cytosol (Trpv1) signal transduction (Tnf)
extracellular space (Tnf) extracellular region (Tnf) intracellular (Tnf)
Tnf (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 7 98.72 Very High Very High Very High
Calcitonin gene-related peptide 1 98.00 Very High Very High Very High
cytokine 2 78.76 Quite High
Hyperalgesia 2 68.04 Quite High
Pain 2 67.36 Quite High
Inflammation 2 65.64 Quite High
Disease Link Frequency Relevance Heat
Cancer 2 75.00 Quite High
Necrosis 2 75.00 Quite High
Hyperalgesia 2 68.04 Quite High
Pain 2 67.36 Quite High
INFLAMMATION 2 65.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This long-term up-regulation of TRPV1 expression by TNFalpha correlated with enhancement in capsaicin-induced calcitonin gene-related peptide release (P<0.05).
TNFalpha Positive_regulation (up-regulation) of Gene_expression (expression) of TRPV1 associated with qutenza and calcitonin gene-related peptide
1) Confidence 0.46 Published 2008 Journal Neuroscience Section Abstract Doc Link 18582539 Disease Relevance 0.48 Pain Relevance 0.77

General Comments

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