INT152879

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp2e1) oxidoreductase activity (Cyp2e1) endoplasmic reticulum (Cyp2e1)
enzyme binding (Cyp2e1)
Anatomy Link Frequency
Brain 2
Cyp2e1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 1 78.08 Quite High
Disease Link Frequency Relevance Heat
Toxicity 3 99.40 Very High Very High Very High
Parkinson's Disease 3 95.28 Very High Very High Very High
Hepatotoxicity 1 76.32 Quite High
Poisoning 1 74.64 Quite High
Targeted Disruption 2 64.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Brain CYP2E1 inhibition by DDC in C57Bl mice was responsible for increased toxicity and striatal MPP(+) accumulation.
Regulation (responsible) of Negative_regulation (inhibition) of CYP2E1 in Brain associated with toxicity
1) Confidence 0.45 Published 2008 Journal Parkinsonism Relat. Disord. Section Abstract Doc Link 18583171 Disease Relevance 0.80 Pain Relevance 0.08

General Comments

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