INT15288

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Context Info
Confidence 0.60
First Reported 1981
Last Reported 2007
Negated 4
Speculated 0
Reported most in Abstract
Documents 11
Total Number 12
Disease Relevance 3.68
Pain Relevance 2.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Hp) extracellular region (Hp) Golgi apparatus (Hp)
endoplasmic reticulum (Hp) response to stress (Hp)
Anatomy Link Frequency
posterior 1
body 1
Hp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 126 100.00 Very High Very High Very High
primary somatosensory cortex 100 99.92 Very High Very High Very High
anesthesia 7 99.40 Very High Very High Very High
Pain 7 98.24 Very High Very High Very High
Cluster headache 8 98.12 Very High Very High Very High
metalloproteinase 8 98.04 Very High Very High Very High
Inflammation 44 97.00 Very High Very High Very High
rheumatoid arthritis 40 94.88 High High
ketamine 2 80.16 Quite High
Angina 1 66.00 Quite High
Disease Link Frequency Relevance Heat
Obesity 6 99.84 Very High Very High Very High
Myocardial Infarction 2 99.60 Very High Very High Very High
Cluster Headache 8 98.44 Very High Very High Very High
Pain 5 98.24 Very High Very High Very High
Abscess 4 97.92 Very High Very High Very High
INFLAMMATION 44 97.00 Very High Very High Very High
Infection 8 96.32 Very High Very High Very High
Rheumatoid Arthritis 40 94.88 High High
Injury 8 82.20 Quite High
Aids-related Complex 70 81.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 14 patients with an according to the WHO-criteria definitive myocardial infarction quantitative serum haptoglobin course controls were performed in the first week after the pain event.
Regulation (controls) of haptoglobin associated with pain and myocardial infarction
1) Confidence 0.60 Published 1981 Journal Z Gesamte Inn Med Section Abstract Doc Link 6805142 Disease Relevance 0.61 Pain Relevance 0.30
Haptoglobin levels were not influenced by age, season, or parasite load.
Neg (not) Regulation (influenced) of Haptoglobin
2) Confidence 0.57 Published 2007 Journal J. Wildl. Dis. Section Abstract Doc Link 17495310 Disease Relevance 0.31 Pain Relevance 0.11
There were no pathologically increased values for serum haptoglobin or orosomucoid in our 9 patients with chronic cluster headache, again significantly less than in our 43 patients with active episodic cluster headache, 51 percent of whom had pathologically increased values of haptoglobin or orosomucoid.
Neg (no) Regulation (values) of haptoglobin associated with cluster headache
3) Confidence 0.26 Published 1991 Journal Headache Section Abstract Doc Link 1720429 Disease Relevance 0.83 Pain Relevance 0.78
As a control, the regulation of LBP, haptoglobin, and S100A9 was confirmed by real-time RT–PCR (Fig. 4a).
Regulation (regulation) of haptoglobin
4) Confidence 0.24 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174937 Disease Relevance 0.16 Pain Relevance 0.13
In conclusion, serum Hp levels correlate to the stable clinical health status observed during captivity, with moderate Hp response during capture and initial acclimation to captivity and acute response to inflammation and infection.
Regulation (response) of Hp associated with inflammation and infection
5) Confidence 0.22 Published 2007 Journal J. Wildl. Dis. Section Abstract Doc Link 17495310 Disease Relevance 0.44 Pain Relevance 0.16
Routine blubber biopsies collected under gas anesthesia did not produce a measurable Hp response.
Neg (not) Regulation (response) of Hp associated with anesthesia
6) Confidence 0.22 Published 2007 Journal J. Wildl. Dis. Section Abstract Doc Link 17495310 Disease Relevance 0.28 Pain Relevance 0.17
In conclusion, serum Hp levels correlate to the stable clinical health status observed during captivity, with moderate Hp response during capture and initial acclimation to captivity and acute response to inflammation and infection.
Regulation (response) of Hp associated with inflammation and infection
7) Confidence 0.22 Published 2007 Journal J. Wildl. Dis. Section Abstract Doc Link 17495310 Disease Relevance 0.46 Pain Relevance 0.17
Meclofenamate (5 mg.kg-1 i.v.) did not significantly affect renal hemodynamics in either HP or LP rats.
Neg (not) Regulation (affect) of HP
8) Confidence 0.14 Published 1990 Journal Circ. Res. Section Abstract Doc Link 2198116 Disease Relevance 0.06 Pain Relevance 0.08
Normalized IEG expression levels in HP did not vary significantly across states.
Regulation (Normalized) of HP associated with hippocampus
9) Confidence 0.10 Published 2007 Journal Frontiers in Neuroscience Section Body Doc Link PMC2577304 Disease Relevance 0.24 Pain Relevance 0.63
Arrays targeting HP, S1, and V1 (Figure 1C) were centered on the following stereotaxic coordinates on the left hemisphere, in mm from Bregma with respect to the antero-posterior (AP), medio-lateral (ML), and dorso-ventral (DV) axes (Paxinos and Watson, 1997): HP (AP: ?
Regulation (targeting) of HP in posterior associated with primary somatosensory cortex and hippocampus
10) Confidence 0.06 Published 2007 Journal Frontiers in Neuroscience Section Body Doc Link PMC2577304 Disease Relevance 0 Pain Relevance 0.31
The values for orosomucoid, haptoglobin, IgG, IgM and tests for rheumatic and antinuclear factors were significantly increased in the obese group compared with normal values at the hospital.
Regulation (values) of haptoglobin
11) Confidence 0.05 Published 1995 Journal Int. J. Obes. Relat. Metab. Disord. Section Body Doc Link 7627247 Disease Relevance 0.08 Pain Relevance 0
2-macroglobulin, and haptoglobin levels were influenced by body mass index [26].
Regulation (influenced) of haptoglobin in body associated with obesity
12) Confidence 0.02 Published 2004 Journal Comp Hepatol Section Body Doc Link PMC449730 Disease Relevance 0.21 Pain Relevance 0.06

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