INT152891

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (JUN) nuclear chromosome (JUN) aging (JUN)
DNA binding (JUN) signal transducer activity (Ptger2) cytosol (JUN)
Ptger2 (Mus musculus)
JUN (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 87.84 High High
agonist 1 60.60 Quite High
cINOD 1 33.24 Quite Low
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Skin Cancer 5 100.00 Very High Very High Very High
Carcinoma 1 75.00 Quite High
Disease 2 45.44 Quite Low
Cancer 1 43.08 Quite Low
INFLAMMATION 1 33.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these data demonstrate for the first time that the EP2 receptor mediates the mitogenic effect of PGE(2) in esophageal squamous cell carcinoma via activation of the Erk/AP-1 pathway.
EP2 receptor Positive_regulation (mediates) of Positive_regulation (activation) of AP-1 associated with skin cancer
1) Confidence 0.00 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18583546 Disease Relevance 0.23 Pain Relevance 0.07

General Comments

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