INT152906

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 5.83
Pain Relevance 2.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl1) extracellular region (Cxcl1)
Anatomy Link Frequency
macrophages 2
mesentery 2
lung 2
Cxcl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 324 100.00 Very High Very High Very High
cytokine 238 100.00 Very High Very High Very High
chemokine 80 100.00 Very High Very High Very High
tolerance 9 96.28 Very High Very High Very High
ischemia 34 95.28 Very High Very High Very High
Inflammatory response 61 90.40 High High
imagery 4 82.96 Quite High
reflex sympathetic dystrophy 3 74.04 Quite High
Antinociceptive 4 67.52 Quite High
Inflammatory stimuli 12 65.28 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 384 100.00 Very High Very High Very High
Urological Neuroanatomy 11 99.84 Very High Very High Very High
Infection 67 98.52 Very High Very High Very High
Disease 27 96.48 Very High Very High Very High
Cv Unclassified Under Development 34 95.28 Very High Very High Very High
Nociception 18 94.80 High High
Edema 9 87.36 High High
Apoptosis 12 83.72 Quite High
Hemorrhage 2 82.12 Quite High
Reperfusion Injury 6 77.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, PAG had no effect on LPS-induced production of the hypernociceptive cytokines, TNF-alpha, IL-1beta and CXCL1/KC and on hypernociception induced by PGE(2), a directly acting hypernociceptive mediator.
Neg (no) Regulation (effect) of Gene_expression (production) of CXCL1 associated with urological neuroanatomy and cytokine
1) Confidence 0.44 Published 2008 Journal Eur. J. Pharmacol. Section Abstract Doc Link 18585702 Disease Relevance 0.51 Pain Relevance 0.12
Consistent with the first experiment, there was a significant effect of mechanical ventilation on lung levels of KC/CXCL1, MCP1/CCL2, MIP1?
Regulation (effect) of Gene_expression (levels) of CXCL1 in lung
2) Confidence 0.44 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC3002319 Disease Relevance 0.44 Pain Relevance 0.25
played a role in regulating the expression of MIP-2 and KC.
Regulation (role) of Gene_expression (expression) of KC
3) Confidence 0.41 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2707360 Disease Relevance 1.09 Pain Relevance 0.23
With the exception of IL-6, KC, and MIP1?
Regulation (With) of Gene_expression (exception) of KC associated with chemokine
4) Confidence 0.33 Published 2007 Journal BMC Immunol Section Body Doc Link PMC1891101 Disease Relevance 0.22 Pain Relevance 0.59
Heparin therapy significantly decreased TAT3 levels but did not alter the profile of GRO-1 or IL-6 protein levels seen with venous occlusion.
Regulation (profile) of Gene_expression (levels) of GRO-1
5) Confidence 0.29 Published 2009 Journal Ann Vasc Surg Section Abstract Doc Link 18640815 Disease Relevance 0.76 Pain Relevance 0.35
I/R-induced changes in KC (CXCL1) and MCP-1 (CCL2) protein expression in the mesentery were paralleled by changes in mRNA levels, as detected by real-time PCR.
Regulation (changes) of Gene_expression (expression) of CXCL1 in mesentery
6) Confidence 0.23 Published 2008 Journal FASEB J Section Body Doc Link PMC2700033 Disease Relevance 0.07 Pain Relevance 0.16
and CXCL-1/KC hypernociceptive roles in carrageenin inflammation were demonstrated to be, at least in part, dependent on the production of IL-1?
Regulation (dependent) of Gene_expression (roles) of CXCL-1 associated with inflammation
7) Confidence 0.22 Published 2010 Journal Mol Pain Section Body Doc Link PMC2959021 Disease Relevance 0.78 Pain Relevance 0.35
Selective antagonism of the C3a receptor significantly attenuated production of MIP-2 and KC, whereas C5a receptor antagonism and prevention of membrane attack complex (MAC) formation did not have a significant effect on MIP-2 and KC production [34].
Regulation (effect) of Gene_expression (production) of KC
8) Confidence 0.22 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 0.64 Pain Relevance 0.24
played a role in regulating the expression of MIP-2 and KC.
Regulation (regulating) of Gene_expression (expression) of KC
9) Confidence 0.18 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2707360 Disease Relevance 1.09 Pain Relevance 0.23
Regulation of FasL expression in KC or macrophages has been achieved in a number of experiments.
Regulation (Regulation) of Gene_expression (expression) of KC in macrophages
10) Confidence 0.07 Published 2004 Journal Comp Hepatol Section Body Doc Link PMC2410251 Disease Relevance 0.22 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox