INT152929

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Context Info
Confidence 0.62
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.18
Pain Relevance 2.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Cldn2) plasma membrane (Cldn2)
Cldn2 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 33 97.98 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 21 99.54 Very High Very High Very High
Apoptosis 3 98.76 Very High Very High Very High
INFLAMMATION 3 70.56 Quite High
Metastasis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, NSAIDs inhibited the invasion and migration activity of cancer cells and this inhibition was suppressed by overexpression of claudin-2.
Positive_regulation (overexpression) of Gene_expression (overexpression) of claudin-2 associated with cancer and cinod
1) Confidence 0.62 Published 2008 Journal Carcinogenesis Section Abstract Doc Link 18586689 Disease Relevance 0.74 Pain Relevance 0.84
Overexpression or suppression of claudin-2 expression caused stimulation or inhibition, respectively, of the invasion and migration activity of cancer cells.
Positive_regulation (Overexpression) of Gene_expression (Overexpression) of claudin-2 associated with cancer
2) Confidence 0.45 Published 2008 Journal Carcinogenesis Section Abstract Doc Link 18586689 Disease Relevance 0.70 Pain Relevance 0.79
In contrast, neither cell growth nor apoptosis induced by lack of anchorage of cancer cells was affected by overexpression or suppression of expression of claudin-2.
Positive_regulation (overexpression) of Gene_expression (expression) of claudin-2 associated with cancer and apoptosis
3) Confidence 0.45 Published 2008 Journal Carcinogenesis Section Abstract Doc Link 18586689 Disease Relevance 0.74 Pain Relevance 0.84

General Comments

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