INT152949

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Homer1, Sgk1) cytoplasm (Homer1, Sgk1) mitochondrion (Sgk1)
endoplasmic reticulum (Sgk1) nucleus (Sgk1) kinase activity (Sgk1)
Homer1 (Mus musculus)
Sgk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 1 99.12 Very High Very High Very High
amygdala 8 91.44 High High
Morphine 2 90.40 High High
opioid receptor 3 89.44 High High
addiction 2 83.48 Quite High
monoamine 1 66.24 Quite High
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 94.60 High High
Targeted Disruption 1 89.80 High High
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A separate quantitative PCR analysis of genes in the last of these groups confirms the dysregulation of both orphan (Gpr88) and known (DrD1A, Adora2A, Cnr1, Grm5, Gpr6) G protein-coupled receptors, scaffolding (PSD95, Homer1) and signaling (Sgk, Cap1) proteins, and neuropeptides (CCK, galanin).
Homer1 Regulation (dysregulation) of Sgk associated with neuropeptide
1) Confidence 0.28 Published 2008 Journal Eur. J. Neurosci. Section Abstract Doc Link 18588537 Disease Relevance 0.18 Pain Relevance 0.76

General Comments

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