INT152982

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Context Info
Confidence 0.37
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 14
Total Number 14
Disease Relevance 9.63
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (ACCS)
Anatomy Link Frequency
monocyte 1
chest 1
heart 1
ACCS (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 122 100.00 Very High Very High Very High
Angina 128 99.28 Very High Very High Very High
Inflammation 45 95.88 Very High Very High Very High
Pain 14 77.28 Quite High
Serotonin 9 73.72 Quite High
Bioavailability 3 71.92 Quite High
Inflammatory response 3 71.28 Quite High
sSRI 27 70.04 Quite High
Opioid 1 68.76 Quite High
ischemia 55 41.32 Quite Low
Disease Link Frequency Relevance Heat
Acute Coronary Syndrome 373 100.00 Very High Very High Very High
Depression 156 100.00 Very High Very High Very High
Stress 37 100.00 Very High Very High Very High
Hypertension 24 100.00 Very High Very High Very High
Heart Disease 21 100.00 Very High Very High Very High
Acute Chest Syndrome 10 100.00 Very High Very High Very High
Compartment Syndromes 8 100.00 Very High Very High Very High
Angina 104 99.28 Very High Very High Very High
Coronary Artery Disease 118 98.76 Very High Very High Very High
Death 96 96.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: In NSTE ACS, an invasive strategy has a comparable benefit in men and high-risk women for reducing the composite end point of death, MI, or rehospitalization with ACS.
Negative_regulation (reducing) of ACS
1) Confidence 0.37 Published 2008 Journal JAMA Section Body Doc Link 18594042 Disease Relevance 0 Pain Relevance 0
Levels of many pharmaceutically active compounds (PhACs) are barely reduced and they are, therefore, detected in WWTP effluents.
Negative_regulation (reduced) of PhACs
2) Confidence 0.26 Published 2006 Journal Anal Bioanal Chem Section Body Doc Link PMC1805043 Disease Relevance 0 Pain Relevance 0.04
We believe that this prediction model, combined with the judgment of trained healthcare personnel, could be useful for the early discharge of chest pain patients in populations with a low prevalence of ACS.
Negative_regulation (prevalence) of ACS in chest associated with acute coronary syndrome and angina
3) Confidence 0.18 Published 2006 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC1559601 Disease Relevance 0.61 Pain Relevance 0.10
Modular prevention of heart disease following acute coronary syndrome (ACS) [ISRCTN42984084]

Background

Negative_regulation (prevention) of ACS in heart associated with acute coronary syndrome and heart disease
4) Confidence 0.16 Published 2006 Journal BMC Cardiovasc Disord Section Title Doc Link PMC1524985 Disease Relevance 1.01 Pain Relevance 0.19
If the care for ACS was delivered over several contiguous hospitalizations involving hospital transfer, the presence of an ICP, HD and the LoS were evaluated for the entire episode.
Negative_regulation (delivered) of ACS associated with acute coronary syndrome and death
5) Confidence 0.15 Published 2005 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1181243 Disease Relevance 0.72 Pain Relevance 0
In a linear regression model predicting perceived stress, including cortisol concentration, age, gender, marital status, CABG, history of depression, and time since most recent ACS, cortisol was not associated with PSS scores (beta = ?
Negative_regulation (predicting) of ACS associated with stress, acute coronary syndrome and depression
6) Confidence 0.15 Published 2010 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2938288 Disease Relevance 1.05 Pain Relevance 0.23
However, in these studies low sensitivity troponins were used, therefore reducing cTnT sensitivity for ACS.
Negative_regulation (reducing) of ACS associated with acute coronary syndrome
7) Confidence 0.04 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.67 Pain Relevance 0.08
CPU patients have a low prevalence of ACS, so a large number of additional patients will need to be tested to detect a small number of additional cases.
Negative_regulation (prevalence) of ACS associated with acute coronary syndrome
8) Confidence 0.04 Published 2005 Journal BMC Emerg Med Section Body Doc Link PMC1201136 Disease Relevance 0.63 Pain Relevance 0
Hence these findings may not apply to more prolonged regimes, or to populations with a higher prevalence of ACS.
Negative_regulation (prevalence) of ACS associated with acute coronary syndrome
9) Confidence 0.04 Published 2005 Journal BMC Emerg Med Section Body Doc Link PMC1201136 Disease Relevance 0.90 Pain Relevance 0.08
The therapeutic benefits that can derive from BNP and NT-proBNP assessment in ACS are not clear.
Negative_regulation (derive) of ACS associated with acute coronary syndrome
10) Confidence 0.04 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.83 Pain Relevance 0.04
3. incidence of cardiovascular events defined as recurrent ACS and unplanned revascularisation;
Negative_regulation (defined) of ACS associated with acute coronary syndrome
11) Confidence 0.03 Published 2009 Journal Trials Section Body Doc Link PMC2674039 Disease Relevance 0.88 Pain Relevance 0.24
There is considerable variation in the literature regarding the design for ACS in animals [51], and recommendations for research regarding IAH and ACS have been published only recently [52].
Negative_regulation (regarding) of ACS associated with compartment syndromes and hypertension
12) Confidence 0.03 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2912801 Disease Relevance 0.46 Pain Relevance 0.07
Overexpression of monocyte Fc receptors may have been a possibility in ACS however.
Negative_regulation (possibility) of ACS in monocyte
13) Confidence 0.02 Published 2004 Journal Immun Ageing Section Body Doc Link PMC544957 Disease Relevance 0.92 Pain Relevance 0.23
Intensive care unit stay postoperatively is recommended by many authors [1–6] for specific reanimation preventing VOC and ACS (oxygen therapy, hydratation, antibiotics monitoring with pulse oximetry).
Negative_regulation (preventing) of ACS associated with acute chest syndrome
14) Confidence 0.01 Published 2009 Journal The Pan African medical journal Section Body Doc Link PMC2984284 Disease Relevance 0.95 Pain Relevance 0

General Comments

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