INT153015

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.90
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Brain 2
nct (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 4 99.84 Very High Very High Very High
Dopamine 2 99.16 Very High Very High Very High
abdominal pain 16 98.12 Very High Very High Very High
Neurotransmitter 30 86.88 High High
antagonist 5 84.56 Quite High
colic 2 76.04 Quite High
agonist 1 39.20 Quite Low
anesthesia 1 25.00 Low Low
imagery 6 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Abdominal Pain 16 98.12 Very High Very High Very High
Hypoxia 7 93.36 High High
Renal Colic 2 76.04 Quite High
Apnoea 1 58.20 Quite High
Ureteral Obstruction 1 48.32 Quite Low
Ileus 2 34.88 Quite Low
Cholecystitis 3 30.52 Quite Low
Diverticulitis 3 29.76 Quite Low
Appendicitis 5 29.12 Quite Low
Targeted Disruption 1 15.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using line scanning confocal microscopy it has been reported that electrically-evoked NCTs can be detected 6 ms after stimulation (Brain et al., 2002), suggesting that the real delay between the sEJP and NCT is much briefer than the range of values, ?
Positive_regulation (briefer) of Gene_expression (sEJP) of NCT in Brain
1) Confidence 0.24 Published 2007 Journal Neuroscience Section Body Doc Link PMC2543106 Disease Relevance 0 Pain Relevance 0.16
RT-PCR assessment of mRNA encoding for adenosine A(1A) and A(2A) receptors, dopamine D(2) receptors, and tyrosine hydroxylase in the rat carotid bodies showed that NCT enhanced mRNA expression levels of adenosine A(2A), dopamine D(2) receptors, and tyrosine hydroxylase of males but not females.
Positive_regulation (levels) of Gene_expression (expression) of NCT associated with dopamine and adenocard
2) Confidence 0.21 Published 2008 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 18596110 Disease Relevance 0.60 Pain Relevance 0.31
In our department NCT was introduced in 2001 instead of APF in patients with acute abdominal pain.
Positive_regulation (department) of Gene_expression (introduced) of NCT associated with abdominal pain
3) Confidence 0.05 Published 2010 Journal Upsala Journal of Medical Sciences Section Body Doc Link PMC2853788 Disease Relevance 0.30 Pain Relevance 0.26

General Comments

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