INT153064

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.52
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hif1a) signal transduction (Hif1a) nucleolus (Hif1a)
nucleus (Hif1a) protein binding transcription factor activity (Hif1a) DNA binding (Hif1a)
Hif1a (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 1 65.64 Quite High
Inflammatory response 1 61.08 Quite High
Disease Link Frequency Relevance Heat
Hypoxia 3 100.00 Very High Very High Very High
Heterotopic Ossification 2 98.60 Very High Very High Very High
Metaplasia 2 97.44 Very High Very High Very High
Disease 10 84.44 Quite High
Calcification 1 70.20 Quite High
Reprotox - General 2 1 67.36 Quite High
Pain 1 65.64 Quite High
INFLAMMATION 1 60.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The up-regulation of hypoxia-inducible factor-1 (HIF-1) leads to an increased downstream expression of HIF-1 target genes, such as TGFbeta and iNOS.
Positive_regulation (leads) of Regulation (regulation) of hypoxia-inducible factor-1 associated with hypoxia
1) Confidence 0.45 Published 2008 Journal Int. J. Biochem. Cell Biol. Section Abstract Doc Link 18599338 Disease Relevance 1.52 Pain Relevance 0.10

General Comments

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