INT15310

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Context Info
Confidence 0.67
First Reported 1989
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 8
Total Number 17
Disease Relevance 20.57
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
brain 1
lining cells 1
DLEU1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory marker 10 97.36 Very High Very High Very High
Inflammation 30 94.00 High High
Enkephalin 10 88.72 High High
substance P 10 87.44 High High
cva 4 81.36 Quite High
Pain 18 78.64 Quite High
abdominal pain 1 75.08 Quite High
Central nervous system 4 75.00 Quite High
imagery 22 72.76 Quite High
pain flank 2 72.40 Quite High
Disease Link Frequency Relevance Heat
Parkinson's Disease 1553 100.00 Very High Very High Very High
Disease 1335 100.00 Very High Very High Very High
Cancer 4 99.76 Very High Very High Very High
Dementia 620 99.56 Very High Very High Very High
Lymphatic System Cancer 3 98.40 Very High Very High Very High
Cyst 7 98.26 Very High Very High Very High
Hypercalcemia 10 97.32 Very High Very High Very High
INFLAMMATION 40 97.04 Very High Very High Very High
Disease Progression 43 96.24 Very High Very High Very High
Alzheimer's Dementia 180 95.08 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tumor cells were negative for Leu-M1 and carcinoembryonic antigen.
Neg (negative) Gene_expression (negative) of Leu-M1 associated with cancer
1) Confidence 0.67 Published 1991 Journal Ultrastruct Pathol Section Abstract Doc Link 1721749 Disease Relevance 0.92 Pain Relevance 0.08
-synuclein in PD and DLB individuals, in comparison to the AD and control groups (P?
Gene_expression (individuals) of DLB associated with parkinson's disease and disease
2) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 2.15 Pain Relevance 0
clinical core features that makes the DLB diagnosis hardly recognisable during life,
Gene_expression (diagnosis) of DLB
3) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Abstract Doc Link PMC2965495 Disease Relevance 0.68 Pain Relevance 0
In comparison to PD, PDD, and AD subjects, the DLB group had the lowest CSF level of A?
Gene_expression (group) of DLB associated with parkinson's disease and disease
4) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 2.32 Pain Relevance 0
peptide 1-42, although characteristic of AD, is also found in DLB and PDD (see [64]; Table 3), and this may reflect the similar extent of A?
Gene_expression (found) of DLB associated with parkinson's disease and disease
5) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 1.32 Pain Relevance 0.03
-synuclein CSF levels was present even in DLB subjects with mild dementia [44], further indicating that lower CSF ?
Gene_expression (subjects) of DLB associated with parkinson's disease and dementia
6) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 1.78 Pain Relevance 0
This is particularly important in DLB, in the light of the difficulties of diagnosing this type of dementia in routine clinical setting.

1.4.

Gene_expression (important) of DLB associated with parkinson's disease and dementia
7) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 1.60 Pain Relevance 0.05
brain deposition between AD and DLB, in terms of the deposition occurring later in the course of DLB [109] or the faster rate of disease progression in DLB [32].In the Bibl et al. [64] study, a novel A?
Gene_expression (deposition) of DLB in brain associated with parkinson's disease, disease and disease progression
8) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 1.89 Pain Relevance 0.03
Clinico-pathological studies have shown that it is the low frequency of DLB
Gene_expression (frequency) of DLB
9) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Abstract Doc Link PMC2965495 Disease Relevance 0.64 Pain Relevance 0
CSF patterns vary between AD, DLB, and PDD, and introduction of A?
Gene_expression (vary) of DLB associated with parkinson's disease and disease
10) Confidence 0.32 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 1.83 Pain Relevance 0
However, in DLB, the interleukin CSF levels, specifically, IL-1?
Gene_expression (levels) of DLB associated with parkinson's disease
11) Confidence 0.28 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 1.94 Pain Relevance 0.42
S protein, Leu1 (103,104), and this information was interpreted to mean that Atm1 exported Fe?
Gene_expression (103,104) of Leu1
12) Confidence 0.24 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.58 Pain Relevance 0
S protein, Leu1 (103,104), and this information was interpreted to mean that Atm1 exported Fe?
Gene_expression (mean) of Leu1
13) Confidence 0.24 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.58 Pain Relevance 0
S protein, Leu1 (103,104), and this information was interpreted to mean that Atm1 exported Fe?
Gene_expression (interpreted) of Leu1
14) Confidence 0.24 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.58 Pain Relevance 0
Immunostaining showed that the cyst lining cells were positive for keratin, vimentin, HBME-1, WT1, and thrombomodulin but negative for carcinoembryonic antigen, B72.3, Leu-M1, and BerEP4.
Neg (negative) Gene_expression (negative) of Leu-M1 in lining cells associated with cyst
15) Confidence 0.08 Published 2000 Journal Arch. Pathol. Lab. Med. Section Abstract Doc Link 10782166 Disease Relevance 0.77 Pain Relevance 0.25
Although BCMs are commonly used in clinical trials, their clinical usefulness is limited due to individual patient variability
Gene_expression (used) of BCMs
16) Confidence 0.08 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2685263 Disease Relevance 0.71 Pain Relevance 0.04
All cases were nonreactive for Leu-M1.
Gene_expression (nonreactive) of Leu-M1
17) Confidence 0.01 Published 1989 Journal Arch. Pathol. Lab. Med. Section Abstract Doc Link 2528337 Disease Relevance 0.28 Pain Relevance 0.07

General Comments

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