INT153120

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gnmt) methyltransferase activity (Gnmt) nucleus (Gnmt)
cytoplasm (Gnmt)
Gnmt (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 6 100.00 Very High Very High Very High
Desipramine 1 99.24 Very High Very High Very High
sSRI 2 98.20 Very High Very High Very High
antidepressant 3 84.48 Quite High
Serotonin 1 82.12 Quite High
Potency 3 56.48 Quite High
Inflammation 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 7 90.48 High High
Pressure Volume 2 Under Development 1 78.96 Quite High
Viral Meningitis 9 45.84 Quite Low
Increased Venous Pressure Under Development 1 36.32 Quite Low
Infection 8 5.68 Low Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Paralysis 2 5.00 Very Low Very Low Very Low
Communicable Diseases 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
N-methyl imipramine (NMI), N-methyl fluoxetine and (NMF) N-N dimethyl fluoxetine (NNDF) were synthesized and compared with desipramine (DES), imipramine (IMI) and fluoxetine (F) in their ability to relax rat aortic rings pre-contracted with 80mM KCl using an isolated bath preparation.
Gene_expression (synthesized) of N-methyl imipramine associated with desipramine and fluoxetine
1) Confidence 0.02 Published 2007 Journal Proc. West. Pharmacol. Soc. Section Abstract Doc Link 18605240 Disease Relevance 0.08 Pain Relevance 0.78
methyl transferase and RNA-dependent RNA polymerase (RdRp) domains [10].
Gene_expression (methyl transferase) of methyl transferase
2) Confidence 0.01 Published 2008 Journal Bioinformation Section Body Doc Link PMC2586131 Disease Relevance 0.09 Pain Relevance 0

General Comments

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