INT153146

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Context Info
Confidence 0.68
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.85
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (AIFM1) mitochondrion (AIFM1) oxidoreductase activity (AIFM1)
nucleus (AIFM1) DNA binding (AIFM1) cytoplasm (AIFM1)
AIFM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 18 93.20 High High
cINOD 6 65.04 Quite High
Inflammation 2 57.00 Quite High
Pain 2 56.32 Quite High
Disease Link Frequency Relevance Heat
Death 12 97.78 Very High Very High Very High
Apoptosis 12 94.04 High High
Alagille Syndrome 4 87.92 High High
Adenocarcinoma 2 87.16 High High
Injury 2 75.68 Quite High
Ulcers 2 60.64 Quite High
INFLAMMATION 4 57.00 Quite High
Pain 2 56.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activation of AIF was evaluated by both Western blotting of the cytosol and mitochondrial extracts as well as by visualization and staining using fluorescence microscopy.
Positive_regulation (activation) of AIF
1) Confidence 0.68 Published 2009 Journal Dig. Dis. Sci. Section Abstract Doc Link 18612824 Disease Relevance 1.02 Pain Relevance 0.47
We then tested whether non-caspase-mediated cell death occurred through an AIF mitochondrial pathway using Western blotting and fluorescence microscopy to determine AIF activation.
Spec (determine) Positive_regulation (activation) of AIF associated with death
2) Confidence 0.40 Published 2009 Journal Dig. Dis. Sci. Section Abstract Doc Link 18612824 Disease Relevance 0.83 Pain Relevance 0.18

General Comments

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