INT153218

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Context Info
Confidence 0.45
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.57
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl9)
Anatomy Link Frequency
lymph node 2
coronary artery 2
Cxcl9 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 32 99.80 Very High Very High Very High
Inflammation 52 99.40 Very High Very High Very High
rheumatoid arthritis 102 98.64 Very High Very High Very High
Osteoarthritis 50 98.40 Very High Very High Very High
chemokine 51 87.76 High High
Angina 2 65.36 Quite High
psoriasis 1 47.36 Quite Low
interstitial cystitis 41 38.68 Quite Low
Arthritis 7 29.68 Quite Low
cINOD 1 16.08 Low Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 16 99.44 Very High Very High Very High
INFLAMMATION 52 99.40 Very High Very High Very High
Rheumatoid Arthritis 102 98.64 Very High Very High Very High
Osteoarthritis 50 98.40 Very High Very High Very High
Cystitis 70 97.24 Very High Very High Very High
Atherosclerosis 4 96.96 Very High Very High Very High
Cv General 3 Under Development 2 65.36 Quite High
Hyperplasia 6 61.84 Quite High
Chronic Disease 2 52.00 Quite High
Disease 29 51.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CYP-induced cystitis in mice led to substantial increases in the expression of CXCL10, CXCL11, and CXCR3 mRNA by urinary bladder leukocytes as well as modest increases in the expression of CXCL9 and CXCR3 transcripts by iliac lymph node lymphocytes than compared to normal, untreated mice (Figure 3A).
Positive_regulation (increases) of Transcription (expression) of CXCL9 in lymph node associated with cystitis
1) Confidence 0.45 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 0.62 Pain Relevance 0.10
Concomitantly, significantly increased mRNA levels of CXCL9 and CXCL10 were also detected in RA synovial tissue.
Positive_regulation (increased) of Transcription (levels) of CXCL9 associated with rheumatoid arthritis
2) Confidence 0.38 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193722 Disease Relevance 1.29 Pain Relevance 0.72
We evaluated mRNA expression and protein production of CCL2, CXCL8, CXCL9, CXCL10, IFN-gamma and IL-10 in vitro as well as the expression of the CCR2 and CXCR3 receptors in peripheral blood mononuclear cells (PBMCs) of patients with coronary artery disease (CAD) and healthy controls in the presence or absence of oxidized LDL (oxLDL).
Positive_regulation (evaluated) of Transcription (expression) of CXCL9 in coronary artery associated with coronary artery disease
3) Confidence 0.09 Published 2009 Journal Int. J. Cardiol. Section Abstract Doc Link 18617279 Disease Relevance 0.69 Pain Relevance 0.26
Patients with CAD showed higher constitutive expression of CCL2, CXCL8, CXCL9, CXCL10 and IFN-gamma mRNA and, after stimulation with oxLDL, higher expression of CCL2 and CXCL8 mRNA than the control group.
Positive_regulation (after) of Transcription (expression) of CXCL9 associated with coronary artery disease
4) Confidence 0.09 Published 2009 Journal Int. J. Cardiol. Section Abstract Doc Link 18617279 Disease Relevance 0.97 Pain Relevance 0.33

General Comments

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