INT153272

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Context Info
Confidence 0.50
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.02
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ccl3) extracellular space (Ccl3) extracellular region (Ccl3)
intracellular (Ccl3) cytoskeleton organization (Ccl3) kinase activity (Ccl3)
Anatomy Link Frequency
T cells 2
Ccl3 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 4 99.76 Very High Very High Very High
Multiple sclerosis 60 97.20 Very High Very High Very High
chemokine 82 89.96 High High
Angina 4 82.96 Quite High
Central nervous system 50 75.68 Quite High
Inflammation 47 74.80 Quite High
Demyelination 12 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 2 99.76 Very High Very High Very High
Demyelinating Disease 78 97.20 Very High Very High Very High
Myocardial Infarction 5 94.44 High High
Acute Coronary Syndrome 3 90.04 High High
Cv General 3 Under Development 4 82.96 Quite High
Coronary Artery Disease 2 80.44 Quite High
Central Nervous System Disease 48 75.68 Quite High
INFLAMMATION 47 74.80 Quite High
Parkinson's Disease 1 66.88 Quite High
Alzheimer's Dementia 1 65.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CCL3 levels are elevated during ACS and released upon ischemia.
Positive_regulation (elevated) of Localization (released) of CCL3 associated with ischemia
1) Confidence 0.50 Published 2008 Journal J. Mol. Cell. Cardiol. Section Abstract Doc Link 18619972 Disease Relevance 1.27 Pain Relevance 0.53
These T cells showed an increased migration towards CCL3 and CCL5, suggesting a functional significance of the altered receptor expression [42,52].
Positive_regulation (increased) of Localization (migration) of CCL3 in T cells
2) Confidence 0.30 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC554759 Disease Relevance 0.75 Pain Relevance 0.26

General Comments

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