INT153321

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.31
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dlg4) protein complex assembly (Dlg4) response to stress (Dlg4)
cytoplasm (Dlg4)
Anatomy Link Frequency
brain 2
Dlg4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 3 98.84 Very High Very High Very High
addiction 7 98.48 Very High Very High Very High
Spinal cord 42 68.52 Quite High
imagery 20 64.44 Quite High
intrathecal 22 8.96 Low Low
Eae 58 5.00 Very Low Very Low Very Low
antagonist 56 5.00 Very Low Very Low Very Low
Inflammation 52 5.00 Very Low Very Low Very Low
Dorsal horn 42 5.00 Very Low Very Low Very Low
withdrawal 38 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Morphine Dependence 2 98.84 Very High Very High Very High
Decapitation 2 58.28 Quite High
Inflammatory Pain 56 5.00 Very Low Very Low Very Low
INFLAMMATION 52 5.00 Very Low Very Low Very Low
Hypersensitivity 32 5.00 Very Low Very Low Very Low
Nociception 20 5.00 Very Low Very Low Very Low
Pain 14 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, PSD-95:GFP overexpression was previously shown to affect synaptic properties and even occlude forms of activity-induced synaptic plasticity [67]–[71].
Positive_regulation (overexpression) of Gene_expression (overexpression) of PSD-95
1) Confidence 0.49 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2693930 Disease Relevance 0 Pain Relevance 0.03
OBJECTIVE: To observe the expression of brain-derived neurotrophic factor (BDNF) and postsynaptic density-95 (PSD-95) in hippocampal CA1 region of rat with morphine dependence for different times and withdrawn for 1 week, and investigate the influence of that morphine dependence is withdrawn on rat hippocampal CA1 area.
Spec (observe) Positive_regulation (observe) of Gene_expression (expression) of PSD-95 in brain associated with addiction and morphine
2) Confidence 0.46 Published 2008 Journal Sichuan Da Xue Xue Bao Yi Xue Ban Section Abstract Doc Link 18630696 Disease Relevance 0.19 Pain Relevance 0.36
N-cadherin and PSD-95 were used as loading controls and markers for crude membrane fraction, whereas ?
Positive_regulation (whereas) of Gene_expression (used) of PSD-95
3) Confidence 0.20 Published 2008 Journal Mol Pain Section Body Doc Link PMC2628655 Disease Relevance 0.06 Pain Relevance 0.07
N-cadherin and PSD-95 were used as loading controls and markers for crude membrane fraction, whereas ?
Positive_regulation (markers) of Gene_expression (used) of PSD-95
4) Confidence 0.20 Published 2008 Journal Mol Pain Section Body Doc Link PMC2628655 Disease Relevance 0.06 Pain Relevance 0.07

General Comments

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