INT153329

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Context Info
Confidence 0.67
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.35
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
bladder 1
Cm9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
intrathecal 3 99.48 Very High Very High Very High
Paracetamol 60 98.80 Very High Very High Very High
Intracerebroventricular 3 96.84 Very High Very High Very High
agonist 1 90.88 High High
cINOD 4 75.04 Quite High
Central nervous system 2 75.00 Quite High
Spinal cord 1 71.12 Quite High
imagery 1 70.76 Quite High
antagonist 3 68.36 Quite High
Pain 23 65.84 Quite High
Disease Link Frequency Relevance Heat
Disease 30 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 100 99.40 Very High Very High Very High
Overdose 62 98.98 Very High Very High Very High
Death 24 98.52 Very High Very High Very High
Aggression 2 94.88 High High
Amputation 201 89.40 High High
Overactive Bladder 4 77.52 Quite High
INFLAMMATION 2 73.60 Quite High
Nociception 1 72.64 Quite High
Pain 21 65.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With intrathecal administration DG041 and CM9 produced a long-lasting and robust inhibition on the VMR response to UBD, whereas with intracerebroventricular injection both compounds elicited only a transient reduction of the VMR response to bladder distension.
Gene_expression (produced) of CM9 in bladder associated with intracerebroventricular and intrathecal
1) Confidence 0.67 Published 2008 Journal Am. J. Physiol. Renal Physiol. Section Abstract Doc Link 18632791 Disease Relevance 0.28 Pain Relevance 0.58
METHOD: Community-dwelling patients over 60 years of age in a Veterans Affairs Medical Center who had a documented ICD-9-CM code for dementia within 12 months of screening and no other dementia codes recorded for 2 preceding years but no aggressive behavior during the 12 months preceding study initiation were assessed every 4 months for 24 months for aggression, depression, pain, patient/caregiver relationship quality (mutuality), involvement in pleasant events, and caregiver burden.
Gene_expression (code) of ICD-9-CM
2) Confidence 0.46 Published 2010 Journal J Clin Psychiatry Section Body Doc Link 20361896 Disease Relevance 0.09 Pain Relevance 0
Fourth, ICD-9-CM codes on clinical indication were not present in 874 (22.2%) patients and thus this information is unavailable in those patients.
Neg (not) Gene_expression (present) of ICD-9-CM
3) Confidence 0.07 Published 2005 Journal BMC Nephrol Section Body Doc Link PMC1079864 Disease Relevance 1.48 Pain Relevance 0
However, as the death rate of these patients were not as high of those patients with gangrene, it is quite likely that the ICD-9-CM codes on clinical indication were not entered in patients without gangrene.
Gene_expression (codes) of ICD-9-CM associated with increased venous pressure under development and death
4) Confidence 0.07 Published 2005 Journal BMC Nephrol Section Body Doc Link PMC1079864 Disease Relevance 1.17 Pain Relevance 0
a) exhaustive medical coding: more than 95% of hospitalizations had at least one valid diagnosis code; the proportion of minimally invasive therapeutic ICD-9-CM procedures was more than 10%;
Gene_expression (procedures) of ICD-9-CM
5) Confidence 0.07 Published 2006 Journal BMC Health Serv Res Section Body Doc Link PMC1552063 Disease Relevance 0.25 Pain Relevance 0.07
The cohort of potential acetaminophen overdose cases was identified by searching for appropriate ICD-9-CM and ICD-10 codes in either the primary or 15 secondary diagnosis fields (Table 1).
Gene_expression (codes) of ICD-9-CM associated with paracetamol, disease and overdose
6) Confidence 0.01 Published 2007 Journal BMC Health Serv Res Section Body Doc Link PMC2174469 Disease Relevance 1.08 Pain Relevance 0.31

General Comments

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