INT153345

Context Info Confidence 0.65 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 3 Disease Relevance 3.62 Pain Relevance 0.19

Anatomy Link Frequency myeloid cell 1 skin 1 Basal cell 1 CELP (Homo sapiens)

Pain Link Frequency Relevance Heat spinal inflammation 4 98.20

Disease Link Frequency Relevance Heat Basal Cell Carcinoma 4 100.00 Skin Cancer 108 99.64 Eczema 6 99.28 Cancer 10 99.04 Tinea 14 98.50 Low Back Pain 4 98.20 Radiodermatitis 4 98.00 Malignant Neoplastic Disease 2 92.48 Disease 2 76.56 Thyroid Disease 2 70.84

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Soluble triggering receptor expressed on myeloid cell-1 (sTREM-1): a new mediator involved in early ankylosing spondylitis.

Gene_expression (expressed) of cell-1 in myeloid cell associated with spinal inflammation

1) Confidence 0.65 Published 2008 Journal J. Rheumatol. Section Title Doc Link 18634145 Disease Relevance 0.10 Pain Relevance 0.19

Basal cell carcinomas were the most frequent tumors arising on chronic radiodermatitis.3 The radiogenic BCCs tend to be multiple and they manifest as conventional nodular BCC, superficial BCC and rarely, fibroepithelioma Pinkus and keloidal types.7 Also, linear BCC can develop rarely in the irradiated areas.19

Gene_expression (carcinomas) of cell in Basal cell associated with radiodermatitis, cancer, skin cancer and basal cell carcinoma

2) Confidence 0.23 Published 2008 Journal Indian Journal of Dermatology Section Body Doc Link PMC2763736 Disease Relevance 2.03 Pain Relevance 0

Incubation period between exposure to ionizing radiation and BCC symptoms is shorter in young patients.89 Radiation exposures to the scalp during childhood for tinea capitis were associated with a four-fold increase in skin cancer, primarily basal cell carcinomas, and a three-fold increase in benign skin tumors.210

Gene_expression (carcinomas) of cell in skin associated with tinea, skin cancer and basal cell carcinoma

3) Confidence 0.23 Published 2008 Journal Indian Journal of Dermatology Section Body Doc Link PMC2763736 Disease Relevance 1.49 Pain Relevance 0

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