INT153458

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ctgf, Il6) extracellular region (Ctgf, Il6) cell differentiation (Ctgf)
aging (Il6) Golgi apparatus (Ctgf) cytosol (Ctgf)
Ctgf (Rattus norvegicus)
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 2 93.76 High High
Chronic pancreatitis 1 68.32 Quite High
fibrosis 1 66.76 Quite High
Inflammation 1 36.56 Quite Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 8 90.24 High High
Cancer 1 84.32 Quite High
Necrosis 1 83.84 Quite High
Fibrosis 3 75.36 Quite High
Pancreatic Cancer 1 69.20 Quite High
Pancreatitis 1 68.32 Quite High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CTGF stimulated binding of NF-kappaB to the IL-6 promoter, and siRNA targeting the NF-kappaB subunit RelA interfered with CTGF-induced IL-6 expression, implicating the NF-kappaB pathway in the mediation of the CTGF effect.
CTGF-induced Positive_regulation (induced) of Gene_expression (expression) of IL-6
1) Confidence 0.34 Published 2008 Journal Cell. Signal. Section Abstract Doc Link 18639630 Disease Relevance 1.03 Pain Relevance 0.15

General Comments

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