INT153516

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Context Info
Confidence 0.57
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PLG) extracellular space (PLG) extracellular region (PLG)
plasma membrane (PLG)
PLG (Homo sapiens)
Pas5a (Mus musculus)
Pain Link Frequency Relevance Heat
Nicotine 11 99.60 Very High Very High Very High
Nucleus accumbens 7 98.56 Very High Very High Very High
Dopamine 5 98.08 Very High Very High Very High
addiction 3 80.08 Quite High
Morphine 1 64.08 Quite High
midbrain 1 45.96 Quite Low
Ventral tegmentum 1 45.32 Quite Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 54.68 Quite High
Nicotine Addiction 4 39.56 Quite Low
Disease 1 34.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, we demonstrated that plasmin activated PAR1 and that nicotine-induced place preference and dopamine release were diminished in PAR1-deficient (PAR1-/-) mice.
plasmin Positive_regulation (activated) of PAR1 associated with dopamine and nicotine
1) Confidence 0.57 Published 2008 Journal Nihon Arukoru Yakubutsu Igakkai Zasshi Section Abstract Doc Link 18646640 Disease Relevance 0.05 Pain Relevance 0.83

General Comments

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