INT153533

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Context Info
Confidence 0.48
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 3.96
Pain Relevance 1.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) signal transduction (Ephb1) extracellular region (NMS)
plasma membrane (Ephb1) cytoplasm (Ephb1)
Anatomy Link Frequency
thalamus 3
dorsal horn 3
NMS (Rattus norvegicus)
Ephb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 15 99.20 Very High Very High Very High
Thalamus 3 98.56 Very High Very High Very High
Anterior cingulate cortex 9 92.64 High High
Hyperalgesia 9 78.16 Quite High
Pain 9 75.20 Quite High
nud 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Neuroleptic Malignant Syndrome 27 100.00 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

24 100.00 Very High Very High Very High
Hyperalgesia 9 78.16 Quite High
Pain 6 75.20 Quite High
Dyspepsia 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western blot analysis revealed significant NMS effect on p-ERK expression in the lumbosacral dorsal horn and thalamus.
NMS Regulation (effect) of Gene_expression (expression) of ERK in thalamus associated with neuroleptic malignant syndrome, dorsal horn and thalamus
1) Confidence 0.48 Published 2009 Journal J. Mol. Neurosci. Section Abstract Doc Link 18649147 Disease Relevance 0.86 Pain Relevance 0.61
Furthermore, a significant interactive effect of NMS and CRD on p-ERK expression was observed in laminae III-IV of the lumbosacral dorsal horn.
NMS Regulation (effect) of Gene_expression (expression) of ERK in dorsal horn associated with neuroleptic malignant syndrome and dorsal horn
2) Confidence 0.48 Published 2009 Journal J. Mol. Neurosci. Section Abstract Doc Link 18649147 Disease Relevance 0.75 Pain Relevance 0.71
Western blot analysis revealed significant NMS effect on p-ERK expression in the lumbosacral dorsal horn and thalamus.
NMS Regulation (effect) of in dorsal horn Gene_expression (expression) of ERK in thalamus associated with neuroleptic malignant syndrome, dorsal horn and thalamus
3) Confidence 0.16 Published 2009 Journal J. Mol. Neurosci. Section Abstract Doc Link 18649147 Disease Relevance 0.86 Pain Relevance 0.61

General Comments

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