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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PRKCI) endosome (PRKCI) vesicle-mediated transport (PRKCI)
plasma membrane (PRKCI) nucleus (PRKCI) cytoskeleton organization (PRKCI)
Anatomy Link Frequency
neurons 1
PRKCI (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 98.66 Very High Very High Very High
opioid receptor 7 98.04 Very High Very High Very High
Intracerebroventricular 1 92.56 High High
Morphine 3 88.72 High High
mu opioid receptor 1 75.00 Quite High
Analgesic 1 66.64 Quite High
nMDA receptor 1 25.00 Low Low
antagonist 1 25.00 Low Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In neurons, the C terminus of the Mu-opioid receptor (MOR) binds to the protein kinase C-interacting protein/histidine triad nucleotide binding protein 1 (PKCI/HINT1) which in turn binds the regulator of G-protein signalling RGSZ1/Z2 (RGSZ) protein.
PKCI Binding (binds) of in neurons associated with kinase c and opioid receptor
1) Confidence 0.36 Published 2008 Journal Cell. Signal. Section Abstract Doc Link 18652891 Disease Relevance 0 Pain Relevance 0.60

General Comments

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