INT153589

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PRKCI, Oprm1) endosome (PRKCI) signal transducer activity (Oprm1)
cytoplasm (PRKCI) cytosol (PRKCI) signal transduction (Oprm1)
Anatomy Link Frequency
neurons 2
PRKCI (Homo sapiens)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 14 100.00 Very High Very High Very High
Kinase C 2 100.00 Very High Very High Very High
Intracerebroventricular 2 90.40 High High
Morphine 6 86.56 High High
mu opioid receptor 2 75.00 Quite High
Analgesic 2 64.48 Quite High
nMDA receptor 2 25.00 Low Low
antagonist 2 25.00 Low Low

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In neurons, the C terminus of the Mu-opioid receptor (MOR) binds to the protein kinase C-interacting protein/histidine triad nucleotide binding protein 1 (PKCI/HINT1) which in turn binds the regulator of G-protein signalling RGSZ1/Z2 (RGSZ) protein.
PKCI Binding (binds) of MOR in neurons associated with kinase c and opioid receptor
1) Confidence 0.06 Published 2008 Journal Cell. Signal. Section Abstract Doc Link 18652891 Disease Relevance 0 Pain Relevance 0.59
In neurons, the C terminus of the Mu-opioid receptor (MOR) binds to the protein kinase C-interacting protein/histidine triad nucleotide binding protein 1 (PKCI/HINT1) which in turn binds the regulator of G-protein signalling RGSZ1/Z2 (RGSZ) protein.
PKCI Binding (binds) of Mu-opioid receptor in neurons associated with kinase c and opioid receptor
2) Confidence 0.06 Published 2008 Journal Cell. Signal. Section Abstract Doc Link 18652891 Disease Relevance 0 Pain Relevance 0.59

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox