INT153696

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GSTM1, Gstt1) cytoplasm (GSTM1, Gstt1) small molecule metabolic process (GSTM1)
GSTM1 (Homo sapiens)
Gstt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 1 82.96 Quite High
Disease Link Frequency Relevance Heat
Injury 9 97.44 Very High Very High Very High
Hepatotoxicity 1 87.44 High High
Bacterial Respiratory Disease 1 82.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: The double-null genotype for GSTT1 and GSTM1 might play a role in determining the susceptibility to develop DILI, as a general mechanism that occurs regardless of the type of drug involved, and predominantly in women.
GSTM1 Spec (might) Binding (genotype) of GSTT1 associated with injury
1) Confidence 0.06 Published 2008 Journal Hepatology Section Abstract Doc Link 18666253 Disease Relevance 0.71 Pain Relevance 0.08

General Comments

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