INT153699

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.54
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MTHFR) small molecule metabolic process (MTHFR) oxidoreductase activity (MTHFR)
cellular amino acid metabolic process (MTHFR)
Anatomy Link Frequency
Blood 1
MTHFR (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 65 99.28 Very High Very High Very High
headache 20 87.88 High High
excitatory amino acid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 82 99.28 Very High Very High Very High
Thrombosis Related Under Development 1 96.32 Very High Very High Very High
Thrombosis 2 92.64 High High
Papilledema 1 90.08 High High
Vomiting 5 89.00 High High
Diplopia 1 88.28 High High
Migraine With Aura 21 82.72 Quite High
Lateral Sinus Thrombosis 1 75.00 Quite High
Stress 9 59.96 Quite High
Neurologic Manifestations 1 10.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blood tests showed elevated homocysteine levels, and coagulation studies revealed a homozygous C677T mutation and a heterozygous A1298C mutation of the methylenetetrahydrofolate reductase (MTHFR) gene.
Regulation (methylenetetrahydrofolate) of MTHFR in Blood
1) Confidence 0.45 Published 2008 Journal Genet. Test. Section Abstract Doc Link 18666857 Disease Relevance 0.71 Pain Relevance 0.09
Gender differences in relation to genotype and phenotype have to be examined in a bigger cohort to look at the effect of MTHFRC677T genotype on migraine clinical symptoms diligently.
Regulation (effect) of MTHFR associated with migraine
2) Confidence 0.44 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2919563 Disease Relevance 0.83 Pain Relevance 0.54

General Comments

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