INT153729

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RYBP) transport (Slc17a5) intracellular (RYBP)
DNA binding (RYBP) transmembrane transport (Slc17a5) cytoplasm (RYBP)
RYBP (Homo sapiens)
Slc17a5 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 12 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hepatotoxicity 3 97.60 Very High Very High Very High
Necrosis 2 86.84 High High
Cancer 1 86.48 High High
Hypoxia 1 81.60 Quite High
Toxicity 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SDS significantly protected APAP-induced hepatotoxicity for SDS improved mouse survival rates better than NAC against a lethal dose of APAP and significantly blocked not only APAP-induced increases of AST, ALT, and TNF-alpha but also APAP-induced GSH depletion and MDA accumulation.
APAP-induced Positive_regulation (increases) of AST associated with paracetamol and hepatotoxicity
1) Confidence 0.02 Published 2008 Journal Biol. Pharm. Bull. Section Abstract Doc Link 18670083 Disease Relevance 0.65 Pain Relevance 0.97

General Comments

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