INT153732

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Context Info
Confidence 0.47
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 3.28
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (SCD) endoplasmic reticulum (SCD)
SCD (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 36 97.56 Very High Very High Very High
corticosteroid 1 84.24 Quite High
Analgesic 2 24.88 Low Low
Opioid 1 12.56 Low Low
addiction 1 6.32 Low Low
anesthesia 12 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Pain score 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sickle Cell Anemia 61 100.00 Very High Very High Very High
Chronic Disease 20 99.68 Very High Very High Very High
Cancer 32 98.76 Very High Very High Very High
Death 3 97.84 Very High Very High Very High
Acute Chest Syndrome 3 97.84 Very High Very High Very High
Pain 36 97.56 Very High Very High Very High
Dysgerminoma 29 91.92 High High
Stroke 3 91.56 High High
Hypertension 1 84.48 Quite High
Renal Failure 1 82.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because of low TRC8 expression in the tumor, we anticipated that SREBP target genes, including HMGCR and SCD1 might be overexpressed.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of SCD1 associated with cancer
1) Confidence 0.47 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2727492 Disease Relevance 0.68 Pain Relevance 0
Treatment advances have now transformed SCD into a chronic disease suffered by children and adults.
Positive_regulation (transformed) of Gene_expression (transformed) of SCD associated with sickle cell anemia and chronic disease
2) Confidence 0.25 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1253526 Disease Relevance 1.58 Pain Relevance 0.10
Evaluation of AHR with methacholine challenge in patients with SCD appears to be well tolerated and may elucidate a cause of SCD morbidity.
Positive_regulation (Evaluation) of Gene_expression (Evaluation) of SCD associated with sickle cell anemia
3) Confidence 0.17 Published 2008 Journal Pediatr. Pulmonol. Section Abstract Doc Link 18671275 Disease Relevance 1.01 Pain Relevance 0.19
System SA exhibits the highest overall order (average SCD = ?
Positive_regulation (overall) of Gene_expression (average) of SCD
4) Confidence 0.07 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1808021 Disease Relevance 0 Pain Relevance 0
System SA exhibits the highest overall order (average SCD = ?
Positive_regulation (average) of Gene_expression (average) of SCD
5) Confidence 0.07 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1808021 Disease Relevance 0 Pain Relevance 0
System SB is slightly less ordered (SCD = ?
Positive_regulation (ordered) of Gene_expression (ordered) of SCD
6) Confidence 0.07 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1808021 Disease Relevance 0 Pain Relevance 0
System SA exhibits the highest overall order (average SCD = ?
Positive_regulation (average) of Gene_expression (overall) of SCD
7) Confidence 0.07 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1808021 Disease Relevance 0 Pain Relevance 0
System SA exhibits the highest overall order (average SCD = ?
Positive_regulation (overall) of Gene_expression (overall) of SCD
8) Confidence 0.07 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1808021 Disease Relevance 0 Pain Relevance 0
System SA exhibits the highest overall order (average SCD = ?
Positive_regulation (System) of Gene_expression (exhibits) of SCD
9) Confidence 0.07 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1808021 Disease Relevance 0 Pain Relevance 0

General Comments

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